公开(公告)号：US20250082666A1

公开(公告)日：2025-03-13

申请号：US18955967

申请日：2024-11-21

Applicant: SOUTHEAST UNIVERSITY

Inventor： Wei HUANG ,  Haibo QIU ,  Ke FANG ,  Jianfeng XIE ,  Ling LIU ,  Yi YANG ,  Ran YANG

IPC: A61K31/7105 ,  A61K9/00 ,  A61P31/04

Abstract: A drug for the prevention or treatment of sepsis is provided. The drug comprises an exosome containing a circRNA MOTOR, and a nucleotide sequence corresponding to the circRNA MOTOR is shown in SEQ ID NO: 1.

公开(公告)号：US20210093816A1

公开(公告)日：2021-04-01

申请号：US17086544

申请日：2020-11-02

Applicant: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. ,  ZHONGDA HOSPITAL SOUTHEAST UNIVERSITY

Inventor： Ling LIU ,  Jinglei LIU ,  Yi YANG ,  Xiaoyong ZHOU ,  Chun PAN ,  Yongsheng YAN ,  Jianfeng XIE ,  Songqiao LIU ,  Haibo QIU

IPC: A61M16/00

Abstract: The disclosure provides a respirator, which includes a ventilation device, configured for providing ventilation airflow to a patient. The respirator further includes a first monitor, configured for monitoring a pressure or a flow velocity with which the ventilation device ventilates the patient, and a second monitor, configured for measuring a pressure change that reflects a self-respiratory effort of the patient. The respirator also includes a processor, configured for identifying an inspiratory trigger moment or an expiratory trigger moment of the patient according to the pressure change that reflects the self-respiratory effort of the patient.

公开(公告)号：US20220218928A1

公开(公告)日：2022-07-14

申请号：US17708037

申请日：2022-03-30

Applicant: ZHONGDA HOSPITAL SOUTHEAST UNIVERSITY ,  SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.

Inventor： Ling LIU ,  Jinglei LIU ,  Jianfeng XIE ,  Xiaoyong ZHOU ,  Jingyuan XU ,  Jun CHEN ,  Yi YANG ,  Xinru ZOU ,  Haibo QIU

IPC: A61M16/00 ,  G16H20/40

Abstract: This disclosure provides a method for evaluating volume responsiveness and a medical device. The medical device includes a respiratory assistance device for providing respiratory support for a patient, and a first sensor for collecting physiological parameters of the patient and a processor. When volume responsiveness evaluation is needed, the processor controls ventilation parameters to switch to a second ventilation parameter that may increase the variation of the intrathoracic pressure of the patient, and then uses a parameter variation capable of reflecting the heartbeat of the patient to evaluate whether the patient is volume responsive.