公开(公告)号：US11298343B2

公开(公告)日：2022-04-12

申请号：US16758986

申请日：2018-10-26

Applicant: ST. JUDE CHILDREN'S RESEARCH HOSPITAL

Inventor： Mitchell J. Weiss ,  Mondira Kundu ,  Christophe Lechauve

IPC: A61K31/7052 ,  A61K31/495 ,  A61K31/4164 ,  A61P7/06 ,  A61K31/436 ,  A61K45/06

Abstract: Methods for removing excess free α-globin in erythroid cells and treating a thalassemia using an agent that activates Unc-51 Like autophagy activating Kinase (ULK) are described.

公开(公告)号：US20200345702A1

公开(公告)日：2020-11-05

申请号：US16758986

申请日：2018-10-26

Applicant: ST. JUDE CHILDREN'S RESEARCH HOSPITAL

Inventor： Mitchell J. Weiss ,  Mondira Kundu ,  Christophe Lechauve

IPC: A61K31/436 ,  A61P7/06

Abstract: Methods for removing excess free α-globin in erythroid cells and treating a thalassemia using an agent that activates Unc-51 Like autophagy activating Kinase (ULK) are described.