公开(公告)号：US09682993B2

公开(公告)日：2017-06-20

申请号：US14650826

申请日：2013-12-09

Applicant: ST. JUDE CHILDREN'S RESEARCH HOSPITAL

Inventor： Thomas R Webb ,  Chandraiah Lagisetti

IPC: C07D493/10 ,  C07D309/10 ,  A61K31/351

CPC classification number: C07D493/10 ,  A61K31/351 ,  C07D309/10

Abstract: In one aspect, the invention relates to compounds having anticancer activity; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders associated with uncontrolled cellular proliferation using the compounds and compositions. This abstract is intended to be used as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

公开(公告)号：US20160009728A1

公开(公告)日：2016-01-14

申请号：US14650826

申请日：2013-12-09

Applicant: ST. JUDE CHILDREN'S RESEARCH HOSPITAL

Inventor： Thomas R Webb ,  Chandraiah Lagisetti

IPC: C07D493/10

CPC classification number: C07D493/10 ,  A61K31/351 ,  C07D309/10

Abstract: In one aspect, the invention relates to compounds having anticancer activity; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders associated with uncontrolled cellular proliferation using the compounds and compositions. This abstract is intended to be used as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract translation: 一方面，本发明涉及具有抗癌活性的化合物; 制备化合物的合成方法; 包含该化合物的药物组合物; 以及使用所述化合物和组合物治疗与不受控制的细胞增殖相关的疾病的方法。 该摘要旨在用作扫描工具，用于在特定技术中进行搜索，而不意在限制本发明。