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公开(公告)号:US20240316114A1
公开(公告)日:2024-09-26
申请号:US18679906
申请日:2024-05-31
Applicant: STEMCELL TECHNOLOGIES CANADA INC.
Inventor: Charis-Patricia Segeritz , Ryan Conder , Michael Riedel
CPC classification number: A61K35/38 , A61L27/3633 , A61L27/3813 , A61L27/54 , A61L2300/434 , A61L2430/28 , G01N33/48
Abstract: A method for obtaining epithelial organoids is provided. In one embodiment, the method comprises culturing one or more epithelial ducts, epithelial duct fragments and/or epithelial stem cells isolated therefrom in contact with an extracellular matrix in the presence of a basal medium, wherein the medium is free of FGF and/or nicotinamide. Organoids obtained by the methods described herein, and uses thereof, are also provided.
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公开(公告)号:US12029764B2
公开(公告)日:2024-07-09
申请号:US16618148
申请日:2018-05-29
Applicant: STEMCELL TECHNOLOGIES CANADA INC.
Inventor: Charis-Patricia Segeritz , Ryan Conder , Michael Riedel
CPC classification number: A61K35/38 , A61L27/3633 , A61L27/3813 , A61L27/54 , A61L2300/434 , A61L2430/28 , G01N33/48
Abstract: A method for obtaining epithelial organoids is provided. In one embodiment, the method comprises culturing one or more epithelial ducts, epithelial duct fragments and/or epithelial stem cells isolated therefrom in contact with an extracellular matrix in the presence of a basal medium, wherein the medium is free of FGF and/or nicotinamide. Organoids obtained by the methods described herein, and uses thereof, are also provided.
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