公开(公告)号：US20230212616A1

公开(公告)日：2023-07-06

申请号：US17625395

申请日：2019-07-08

Applicant: SYMRISE AG

Inventor： Dirk FABRITIUS ,  Stefan LAMBRECHT ,  Johannes PANTEN ,  Marcus EH

IPC: C12P7/02 ,  C12P7/26 ,  C12N9/04

CPC classification number: C12P7/02 ,  C12P7/26 ,  C12N9/0006 ,  C12Y101/0105

Abstract: The present invention relates to a method for the stereo selective production of a trans-diol or a cis-diol or a hydroxyketone comprising the step(s) (i) conversion of a trans-diol or a cis-diol to a hydroxyketone and/or (ii) conversion of a hydroxyketone to a cis-diol or a trans-diol, catalyzed by an enzyme, which is encoded by a nucleic acid sequence of SEQ ID NO: or wherein the enzyme comprises an amino acid sequence of SEQ ID NO: 2. The present invention also relates to the use of an enzyme encoded by a nucleic acid sequence of SEQ ID NO: 1 or wherein the enzyme comprises an amino acid sequence of SEQ ID NO: 2 for the conversion of a trans-diol to a cis-diol or for the conversion of a trans-diol or a cis-diol to a hydroxyketone and/or the conversion of a hydroxyketone to a trans-diol or a cis-diol.