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公开(公告)号:US20220153670A1
公开(公告)日:2022-05-19
申请号:US17527465
申请日:2021-11-16
发明人: Chris D. Gerlach , Paul F. Sullivan , Charles F. Palmer, JR. , Andrew K. Tobias, JR. , Edward T. Borish , Brad P. Keown , Nora E. H. Bridenstine , James T. Tanner
IPC分类号: C07C43/285 , A61K47/08 , A61K36/185 , A61P29/00 , C07D311/80 , A61K47/22
摘要: Provided herein is a compound which is particularly suitable for use as a cannabinoid, as an emulsifier for a cannabinoid, in a formulation comprising the compound and in a method of treatment using the compound. The compound is defined by the General Formula: wherein: R1-R10 are independently selected from H or an alkyl of 1-10 carbons; alkenyl of up to 10 carbons; or groups on adjacent carbons may be taken together to form an alkene; R11 and R12 are independently H or —(CH2CHR16O)x—R17 with the proviso that at least one of R11 or R12 represents —(CH2CHR16O)xR17—; R11 and R10 may be taken together to represent —C(R19)2—; R13-R15 independently represent H or an alkyl of 1-8 carbons; each R16 independently represents H or an alkyl of 1-3 carbons; each R17 independently represents H, an alkyl or substituted alkyl of 1-22 carbons, aryl or substituted aryl or the ester of an acid; each R19 independently represents H or an alkyl of 1-5 carbons; and each x is independently an integer of 1-100.