公开(公告)号：US20090048210A1

公开(公告)日：2009-02-19

申请号：US12251114

申请日：2008-10-14

申请人： Saburo MINAMI ,  Yoshiharu OKAMOTO

发明人： Saburo MINAMI ,  Yoshiharu OKAMOTO

IPC分类号： A61K31/70 ,  A61P17/02

CPC分类号： A61K31/7008 ,  A61K31/722

摘要： The present invention has an object of revealing an epidermis regeneration effect of various chitin derivatives and providing an agent for therapy or treatment for wound which can be clinically used effectively. According to the present invention, it has been evidenced that N-acetyl-D-glucosamine has an effect of promoting proliferation of an epidermis keratinized cell. Accordingly, the present invention provides a proliferation promoting agent for epidermis keratinized cell comprising N-acetyl-D-glucosamine. According to another aspect of the present invention, there is provided a regeneration promoting agent or protecting agent for epithelium, skin or dermis comprising the proliferation promoting agent. Further, a therapeutic agent for wound is provided.

摘要翻译： 本发明的目的是揭示各种几丁质衍生物的表皮再生作用，并提供可有效临床使用的伤口治疗或治疗剂。 根据本发明，证明N-乙酰基-D-葡糖胺具有促进表皮角化细胞增殖的作用。 因此，本发明提供了包含N-乙酰基-D-葡糖胺的表皮角化细胞增殖促进剂。 根据本发明的另一方面，提供了包含增殖促进剂的用于上皮，皮肤或真皮的再生促进剂或保护剂。 此外，提供了一种用于伤口的治疗剂。