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1.
公开(公告)号:US20070218130A1
公开(公告)日:2007-09-20
申请号:US11546548
申请日:2006-10-12
CPC分类号: A61K31/66 , A61K9/2013 , A61K9/2018 , A61K9/2054
摘要: The present invention is generally directed to pharmaceutical compositions and process for the preparation of same which are suitable for oral administration to a human patient, comprising: a pharmaceutically-acceptable salt of 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid; a non-reducing sugar diluent; a binder; a disintegrant; and a lubricant, and various other excipients.
摘要翻译: 本发明一般涉及药物组合物及其制备方法,其适合于向人类患者口服,包括:4-氨基-1-羟基亚丁基-1,1-二膦酸的药学上可接受的盐; 非还原糖稀释剂; 粘合剂 崩解剂 和润滑剂,以及各种其它赋形剂。
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公开(公告)号:US06221390B1
公开(公告)日:2001-04-24
申请号:US08920219
申请日:1997-08-25
申请人: Salah U. Ahmed , Gandha Naringrekar
发明人: Salah U. Ahmed , Gandha Naringrekar
IPC分类号: A61K964
CPC分类号: A61K9/1617 , A61K9/5084 , Y10S514/96 , Y10S514/962
摘要: A novel pharmaceutical combination is described, together with a method of making the same and a method of treating hypertensive patients using the same, wherein (1) the pharmaceutically active antihypertensive agent and citric acid and (2) the pharmaceutically active antikaliuretic agent and a nonionic surfactant are mixed, either together or separately, to form an essentially homogenous combination composition, and only thereafter blending with excipients to form the novel combination composition in solid dosage form.
摘要翻译: 本发明描述了一种新型药物组合及其制备方法以及使用其的治疗高血压患者的方法,其中(1)药学活性抗高血压药和柠檬酸和(2)药用活性抗利尿剂和非离子表面活性剂 将表面活性剂一起或分开混合以形成基本均匀的组合组合物,然后仅与赋形剂混合以形成固体剂型的新型组合组合物。
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