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公开(公告)号:US5153349A
公开(公告)日:1992-10-06
申请号:US601767
申请日:1990-10-19
申请人: Sandor Zoltan , Gyorgy Hidasi , Bela Bertok , Istavan Szekely , Janis Hajimichael , Sandor Botar , Lajos Nagy , Eva Somfai , Istvan Lak , Andras Rapi , Antal Gajary , Agnes Hegedus , Maria Tary
发明人: Sandor Zoltan , Gyorgy Hidasi , Bela Bertok , Istavan Szekely , Janis Hajimichael , Sandor Botar , Lajos Nagy , Eva Somfai , Istvan Lak , Andras Rapi , Antal Gajary , Agnes Hegedus , Maria Tary
IPC分类号: A01N53/00 , C07C255/14
CPC分类号: A01N53/00
摘要: The invention relates to a process for the preparation of such isomer mixtures of cypermethrine of the Formula (I) ##STR1## wherein carbon atoms indicated by 1, 3 and .alpha. stand for a chiral carbon atom and the wavy line indicates cis or trans configuration related to the cyclopropane ring--which contains out of the theoretically possible 8-isomers of cypermethrine at least 95% of 1RtransS and 1StransR (Ib) isomer pair or only a mixture of 1RcisC and 1ScisR (Ia) and the isomer pair (Ib) of the ratio (Ia):(Ib)=55:45-25:75 by asymmetric transformation of second order performed in the presence of an amine base and solvent from a starting cypermethrine isomer mixture which contains next to the isomer pair (Ib) cis and other trans isomers or the isomer pair Ia+Ib at an undesired ratio.
摘要翻译: PCT No.PCT / HU90 / 00006 Sec。 371 1990年10月19日第 102(e)1990年10月19日PCT PCT 1990年1月17日PCT公布。 出版物WO90 / 08132 日本1990年7月26日。本发明涉及一种制备式(I)的氯氰菊酯的异构体混合物的方法,其中由1,3和α表示的碳原子代表手性碳原子 并且波浪线表示与环丙烷环有关的顺式或反式构型,其中含有理论上可能的氯氰菊酯的8-异构体至少95%的1RtransS和1StransR(Ib)异构体对,或仅包含1RcisC和1ScisR(Ia )和通过在胺碱和溶剂的存在下由起始氯氰菊酯异构体混合物进行的二级的不对称转化,比率(Ia):(Ib)= 55:45-25:75的异构体对(Ib)= 55:45-25: 异构体对(Ib)顺式和其他反式异构体或异构体对Ia + Ib处于不期望的比例。