公开(公告)号：US20090232919A1

公开(公告)日：2009-09-17

申请号：US12087038

申请日：2007-01-05

申请人： Sang Geon Kim ,  Sang Chan Kim ,  Young Woo Kim

发明人： Sang Geon Kim ,  Sang Chan Kim ,  Young Woo Kim

IPC分类号： A61K36/48 ,  A61K31/352 ,  A61P1/16 ,  C07D311/30

CPC分类号： A61K36/484 ,  A23L33/10 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/352 ,  A23V2250/28 ,  A23V2250/0644 ,  A23V2250/21 ,  A23V2250/032

摘要： The present invention is related to a composition comprising an extract of licorice or liquiritigenin isolated therefrom significantly decrease the blood concentration of LDH and ALT enzyme, central necrosis and inflammation in acetaminophen-induced hepato-toxicity animal model when the inventive extract or compound of the present invention was orally and intravenously administrated thereto. Accordingly, the inventive compositions according to the present invention are useful in the prevention and treatment of the liver diseases and can be used as safe and efficient hepato-protective

摘要翻译： 本发明涉及包含甘草或甘草素的提取物的组合物，当本发明的提取物或本发明的提取物或化合物时，显着降低对乙酰氨基酚诱导的肝毒性动物模型中的LDH和ALT酶的血液浓度，中枢坏死和炎症 对其进行口服和静脉内施用。 因此，根据本发明的本发明组合物可用于预防和治疗肝脏疾病，并且可以用作安全和有效的肝保护