公开(公告)号：US20070009570A1

公开(公告)日：2007-01-11

申请号：US11482393

申请日：2006-07-06

申请人： Sang Heon Kim ,  Soo Hyun Kim ,  Young Ha Kim ,  Jae Hyun Kwon ,  Min Sub Chung

发明人： Sang Heon Kim ,  Soo Hyun Kim ,  Young Ha Kim ,  Jae Hyun Kwon ,  Min Sub Chung

IPC分类号： A61F2/00 ,  B28B1/08

CPC分类号： A61L27/507 ,  A61L27/18 ,  A61L27/20 ,  A61L27/56 ,  C08L67/04 ,  C08L5/00

摘要： The present invention relates to a method of preparing a porous polymer scaffold for tissue engineering using a gel spinning molding technique. The method of the present invention can prepare a porous polymer scaffold having a uniform pore size, high interconnectivity between pores and mechanical strength, as well as high cell seeding and proliferation efficiencies, which can be effectively used in tissue engineering applications. Further, the method of the present invention can easily mold a porous polymer scaffold in various types such as a tube type favorable for regeneration of blood vessels, esophagus, nerves and the like, as well as a sheet type favorable for regeneration of skins, muscles and the like, by regulating the shape and size of a template shaft.

摘要翻译： 本发明涉及使用凝胶纺丝成型技术制备用于组织工程的多孔聚合物支架的方法。 本发明的方法可以制备具有均匀的孔径，孔之间的高互连性和机械强度的多孔聚合物支架，以及可以有效地用于组织工程应用中的高细胞接种和增殖效率。 此外，本发明的方法可以容易地模制多种类型的多孔聚合物支架，例如有利于血管，食管，神经等的再生的管型，以及有利于皮肤，肌肉再生的片状 通过调节模板轴的形状和尺寸。