公开(公告)号：US5185460A

公开(公告)日：1993-02-09

申请号：US872868

申请日：1992-04-22

申请人： Seiji Tazaki ,  Nobuhiro Umeda ,  Nobuo Matsui ,  Tomio Yagihara ,  Katsunori Mikuma

发明人： Seiji Tazaki ,  Nobuhiro Umeda ,  Nobuo Matsui ,  Tomio Yagihara ,  Katsunori Mikuma

IPC分类号： C07C323/25

CPC分类号： C07C323/25

摘要： Aminoacetonitrile derivatives, where the 2-position of aminoacetonitrile is optionally substituted by alkylthio groups, arylthio groups and heterocyclicthio groups. The process for making such compounds comprises reacting hydrogen cyanide with the desired corresponding R-S-H and recovering the crystallized salt thereof. The aminoacetonitrile derivatives are useful as starting materials to produce pharmaceutical and agricultural intermediates such as benzomide derivatives with fungicidal and herbicidal activities.

摘要翻译： 氨基乙腈衍生物，其中氨基乙腈的2-位任选被烷硫基，芳硫基和杂硫基取代。 制备这种化合物的方法包括使氰化氢与所需的相应的R-S-H反应并回收其结晶盐。 氨基乙腈衍生物可用作产生药物和农业中间体的原料，例如具有杀真菌和除草活性的苯甲酰胺衍生物。

公开(公告)号：US4990630A

公开(公告)日：1991-02-05

申请号：US398969

申请日：1989-08-28

申请人： Katsunori Mikuma ,  Nobuhiro Umeda ,  Tomio Yagihara ,  Isami Hamamoto

发明人： Katsunori Mikuma ,  Nobuhiro Umeda ,  Tomio Yagihara ,  Isami Hamamoto

IPC分类号： C07C323/27 ,  C07C67/00 ,  C07C313/00 ,  C07C319/14 ,  C07C321/18 ,  C07C321/28 ,  C07C323/24 ,  C07C323/31 ,  C07D307/38 ,  C07D307/91 ,  C07D333/18 ,  C07D333/34 ,  C07D521/00

CPC分类号： C07D307/38

摘要： The present invention relates to a 2,3-diaminoacrylonitrile derivative or salts thereof, having the formula ##STR1## wherein R represents an alkyl group (which may be substituted by unsubstituted or substituted phenyl groups, halogen atoms, C.sub.1-6 alkoxycarbonyl groups, carboxy groups, C.sub.1-6 alkoxycarbonyl C.sub.1-6 alkylthio groups, hydroxy groups, mercapto groups, cycloalkyl groups or heterocyclic groups containing oxygen atoms); an alkenyl group; a cycloalkyl group; an aryl group (which may be substituted by halogen atoms, C.sub.1-6 alkyl groups, nitro-groups, unsubstituted or substituted phenyl or phenoxy groups or heterocyclic groups containing oxygen atoms or sulfur atoms).The 2,3-diaminoacrylonitrile derivative can be used as starting materials for the production of pharmaceutical and/or agricultural intermediates such as cyanoimidazoles, cyanopyrazines or other cyano-substituted heterocycles.

公开(公告)号：US3971820A

公开(公告)日：1976-07-27

申请号：US526631

申请日：1974-11-25

申请人： Tatsumi Kobayashi ,  Eiji Nishiwaki ,  Shigeharu Yamazoe ,  Mitsuyuki Hoshino ,  Sadafumi Yoshino ,  Katsunori Mikuma

发明人： Tatsumi Kobayashi ,  Eiji Nishiwaki ,  Shigeharu Yamazoe ,  Mitsuyuki Hoshino ,  Sadafumi Yoshino ,  Katsunori Mikuma

IPC分类号： C07C120/00 ,  C07C121/30

CPC分类号： C07C255/00

摘要： A process for tetramerizing hydrogen cyanide to diaminomaleonitrile, wherein hydrogen cyanide is polymerized in an organic solvent in the presence of a basic catalyst and a cocatalyst of the group consisting of organic mercaptans and organic disulfides.

摘要翻译： 将氰化氢四聚化为二氨基马来腈的方法，其中在碱性催化剂和由有机硫醇和有机二硫化物组成的组的助催化剂存在下，在有机溶剂中使氰化氢聚合。