公开(公告)号：US20210308102A1

公开(公告)日：2021-10-07

申请号：US17266813

申请日：2019-08-08

申请人： Seinda Pharmaceutical Guangzhou Corporation

发明人： Hui Ouyang ,  Min Xia

IPC分类号： A61K31/407 ,  A61K31/165 ,  A61K31/661 ,  A61K9/00 ,  A61K31/437 ,  A61K31/222 ,  A61K31/498 ,  A61K31/4168 ,  A61P27/06

摘要： The present disclosure is directed to compositions and methods for treating presbyopia. The compositions can include a cholinesterase inhibitor, such as neostigmine, echothiophate, diisopropyl fluorophosphates, or physostigmine, and/or a mitoic agent. The compositions can act alone or synergistically, for example, to improve the accommodative and focusing ability of the eye while minimizing the side effects from each compound.

公开(公告)号：US12102628B2

公开(公告)日：2024-10-01

申请号：US17706225

申请日：2022-03-28

申请人： Seinda Pharmaceutical Guangzhou Corporation

发明人： Hui Ouyang ,  Yong Qiu

IPC分类号： A61P27/02 ,  A61K9/00 ,  A61K31/06 ,  A61K31/216 ,  A61K31/222 ,  A61K31/24 ,  A61K31/4168 ,  A61K31/417 ,  A61K31/439 ,  A61K31/4406 ,  A61K31/46 ,  A61K31/498 ,  A61K31/551 ,  A61K31/5513 ,  A61P27/10 ,  C07C217/20 ,  C07C219/10 ,  C07D213/04 ,  C07D235/02 ,  C07D403/04 ,  C07D403/12 ,  C07D471/08 ,  C07D487/04 ,  C07D491/18

CPC分类号： A61K31/46 ,  A61K9/0048 ,  A61K31/24 ,  A61K31/4168 ,  A61K31/417 ,  A61K31/498 ,  A61K31/551 ,  A61P27/10

摘要： Compositions and methods useful in slowing, inhibiting, or regressing the progression of myopia, while minimizing pupil dilation and light sensitivity are provided herein. Provided compositions can include a muscarinic receptor antagonist and a miotic agent.

公开(公告)号：US20230062844A1

公开(公告)日：2023-03-02

申请号：US17706225

申请日：2022-03-28

申请人： Seinda Pharmaceutical Guangzhou Corporation

发明人： Hui Ouyang ,  Yong Qiu

IPC分类号： A61K31/46 ,  A61P27/10 ,  A61K9/00 ,  A61K31/24 ,  A61K31/4168 ,  A61K31/417 ,  A61K31/498 ,  A61K31/551

摘要： Compositions and methods useful in slowing, inhibiting, or regressing the progression of myopia, while minimizing pupil dilation and light sensitivity are provided herein. Provided compositions can include a muscarinic receptor antagonist and a miotic agent.

公开(公告)号：US11285141B2

公开(公告)日：2022-03-29

申请号：US16632105

申请日：2018-07-20

申请人： Seinda Pharmaceutical Guangzhou Corporation

发明人： Hui Ouyang ,  Yong Qiu

IPC分类号： A61K31/46 ,  A61K31/4168 ,  A61K31/417 ,  A61K31/551 ,  A61K31/498 ,  A61K31/24 ,  A61K31/465 ,  A61K31/496 ,  A61K31/443 ,  A61K31/4025 ,  A61K31/4409 ,  A61K31/5513 ,  A61K31/222 ,  A61K9/00 ,  A61K45/06 ,  A61P27/02 ,  A61P27/10

摘要： Compositions and methods useful in slowing, inhibiting, or regressing the progression of myopia, while minimizing pupil dilation and light sensitivity are provided herein. Provided compositions can include a muscarinic receptor antagonist and a miotic agent.