专利检索 ap:("Shanghai Cellular Biopharmaceutical Group Ltd.") AND inv:"Jia LI" 第 1 页

1.

发明公开
METHODS FOR PREPARING TUMOR-INFILTRATING LYMPHOCYTES 审中-公开

公开(公告)号：US20240060041A1

公开(公告)日：2024-02-22

申请号：US18259611

申请日：2021-12-29

申请人： Shanghai Cellular Biopharmaceutical Group Ltd.

发明人： Jia LI , Jiyan HOU , Zizhen GONG , Yijie QU , Shichao QIN , Shenchen WANG , Wangqin SHU , Junfeng WU , Fei WANG , Li ZHANG

IPC分类号： C12N5/078 , A61P35/00

CPC分类号： C12N5/0634 , A61P35/00 , C12N2501/2307 , C12N2501/2315 , C12N2501/2321 , C12N2501/734 , C12N2501/73 , C12N2501/2302

摘要： Provided are methods for expanding tumor-infiltrating lymphocytes (TILs), which include co-culturing an initial cell population containing TILs with first feeder cells to obtain a first expanded cell population; and then co-culturing the first expanded cell population with second feeder cells to obtain an expanded TIL population. The methods can quickly produce a large number of TILs from a small tumor sample.