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1.发明申请Water-Soluble Derivatives and Prodrugs of Acacetin and Methods of Making and Using Thereof 有权醋酸乙酸的水溶性衍生物和前药及其制备和使用方法公开(公告)号：US20150218193A1
公开(公告)日：2015-08-06
申请号：US14171228
申请日：2014-02-03
Inventor： Gui-Rong Li , Feng Lin
IPC: C07F9/655
CPC classification number: C07F9/65522
Abstract: Water-soluble derivatives and/or prodrugs of acacetin are described herein. The compounds can be used as cardioprotection agents against myocardial infarction induced by ischemia-reperfusion. In one embodiment the compounds are used to treat ischemic cardiac diseases. In the preferred embodiment, the compounds are used to treat and/or prevent myocardial infarction in humans.
Abstract translation: 本文描述了Acacetin的水溶性衍生物和/或前药。 该化合物可用作心肌保护剂，用于预防缺血再灌注引起的心肌梗死。 在一个实施方案中，化合物用于治疗缺血性心脏病。 在优选的实施方案中，化合物用于治疗和/或预防人心肌梗死。
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2.发明授权Water-soluble derivatives and prodrugs of acacetin and methods of making and using thereof 有权acacetin的水溶性衍生物和前药及其制备和使用方法公开(公告)号：US09260461B2
公开(公告)日：2016-02-16
申请号：US14171228
申请日：2014-02-03
Inventor： Gui-Rong Li , Feng Lin
IPC: A61K31/35 , C07D311/00 , C07F9/655
CPC classification number: C07F9/65522
Abstract: Water-soluble derivatives and/or prodrugs of acacetin are described herein. The compounds can be used as cardioprotection agents against myocardial infarction induced by ischemia-reperfusion. In one embodiment the compounds are used to treat ischemic cardiac diseases. In the preferred embodiment, the compounds are used to treat and/or prevent myocardial infarction in humans.
Abstract translation: 本文描述了Acacetin的水溶性衍生物和/或前药。 该化合物可用作心肌保护剂，用于预防缺血再灌注引起的心肌梗死。 在一个实施方案中，化合物用于治疗缺血性心脏病。 在优选的实施方案中，化合物用于治疗和/或预防人心肌梗死。
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