公开(公告)号：US20230054304A1

公开(公告)日：2023-02-23

申请号：US17783796

申请日：2020-12-10

申请人： Shanghai Zhimeng Biopharma, Inc.

发明人： Bo LIANG ,  Huanming CHEN ,  Gang LIU ,  Zhijun ZHANG ,  Tian XIA ,  Bo HUA ,  Qiu JIN

IPC分类号： C07D413/04 ,  C07F9/6584 ,  C07D413/14 ,  C07H13/10 ,  C07D263/58 ,  C07D493/04 ,  C07D265/18 ,  C07D498/10

摘要： Disclosed are a compound having a neuroprotective effect, a preparation method therefor and a use thereof. Specifically, the compound has the structure shown by formula I, the definition of each group and substituent being as described in the description. Further disclosed are a preparation method for the compound and a use thereof for neuroprotection.

公开(公告)号：US20220227713A1

公开(公告)日：2022-07-21

申请号：US17614780

申请日：2020-05-26

申请人： Shanghai Zhimeng Biopharma Inc.

发明人： Bo LIANG ,  Qiu JIN ,  Huanming CHEN ,  Zhijun ZHANG ,  Bo HUA

IPC分类号： C07D223/16 ,  C07D409/06

摘要： A tetrahydro-1H-benzazepine compound as a potassium channel modulator, a preparation method, and a medicament containing the compound are provided. Specifically, the compound has the structure shown by formula A, in which the definitions of each group and substituent are described in the description. A preparation method for the compound and its use as potassium channel modulator are also described.

公开(公告)号：US20220340563A1

公开(公告)日：2022-10-27

申请号：US17636164

申请日：2020-08-12

申请人： Shanghai Zhimeng Biopharma, Inc.

发明人： Bo LIANG ,  Qiu JIN ,  Huanming CHEN ,  Zhijun ZHANG ,  Tian XIA ,  Bo HUA ,  Gang LIU

IPC分类号： C07D471/04

摘要： 2-aminopyrimidine compounds and pharmaceutical compositions and uses thereof are provided. Specifically, the 2-aminopyrimidine compounds have a structure as shown in formula I. The compounds are suitable for use in the fields of anti-virus and anti-infection, as well as treatment of diseases such as autoimmune diseases and tumors.