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公开(公告)号:US20100093645A1
公开(公告)日:2010-04-15
申请号:US10586269
申请日:2005-01-18
申请人: Shaomeng Wang , Halying Sun , Zaneta Nikolovska-Coleska , Chao-Yie Yang , Liang Xu , Jlanyong Chen
发明人: Shaomeng Wang , Halying Sun , Zaneta Nikolovska-Coleska , Chao-Yie Yang , Liang Xu , Jlanyong Chen
CPC分类号: C07K5/0806 , A61K38/00 , C07K5/0808
摘要: The invention relates to peptidomimetics of Smac which function as inhibitors of Inhibitor of Apoptosis Proteins. The invention also relates to the use of these peptidomimetics for inducing apoptotic cell death and for sensitizing cells to inducers of apoptosis.
摘要翻译: 本发明涉及作为细胞凋亡蛋白抑制剂抑制剂的Smac的肽模拟物。 本发明还涉及这些肽模拟物用于诱导凋亡性细胞死亡和使细胞对细胞凋亡诱导剂敏感的用途。