公开(公告)号：US20160244417A1

公开(公告)日：2016-08-25

申请号：US15027271

申请日：2014-10-03

申请人： Shawn STACHEL ,  Jing LI ,  Anthony GINNETTI

发明人： Shawn Stachel ,  Daniel V. Paone ,  Jing Li ,  Anthony Ginnetti ,  John Lim ,  Jianmin Fu ,  Shimin Xu

IPC分类号： C07D277/30 ,  A61K31/541 ,  C07D417/04 ,  A61K31/5377 ,  C07D277/52 ,  C07D417/10 ,  A61K31/427 ,  C07D277/34 ,  C07D417/14 ,  A61K31/4439 ,  A61K45/06 ,  C07D263/32

CPC分类号： C07D277/30 ,  A61K31/415 ,  A61K31/427 ,  A61K31/44 ,  A61K31/4439 ,  A61K31/5377 ,  A61K31/541 ,  A61K45/06 ,  C07D231/12 ,  C07D263/22 ,  C07D263/32 ,  C07D277/22 ,  C07D277/34 ,  C07D277/52 ,  C07D405/04 ,  C07D417/04 ,  C07D417/10 ,  C07D417/14 ,  Y02A50/423 ,  A61K2300/00

摘要： This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.