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公开(公告)号：US20240226129A1
公开(公告)日：2024-07-11
申请号：US18528550
申请日：2023-12-04
Applicant: Shuttle Pharmaceuticals, Inc.
Inventor： Scott Grindrod , Mira Jung , Olga Timofeeva , Milton Brown , Anatoly Dritschilo
IPC: A61K31/7072 , A61K31/513 , A61K33/243
CPC classification number: A61K31/7072 , A61K31/513 , A61K33/243 , A61K2121/00
Abstract: Methods and formulations are provided for treating cancer and neoplastic diseases in conjunction with radiation therapy where such methods and formulations include a combination of a radiosensitizing agent that is metabolized by thymidine phosphorylase and a thymidine phosphorylase inhibitor that increases the half-life of the radiosensitizing agent.
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公开(公告)号：US20220363652A1
公开(公告)日：2022-11-17
申请号：US17851882
申请日：2022-06-28
Applicant: Shuttle Pharmaceuticals, Inc.
Inventor： Scott Grindrod , Mira Jung , Anatoly Dritschilo
IPC: C07D285/135 , C07C237/20
Abstract: Selective HDAC inhibitors, and pharmaceutical compositions that include the same, are described herein for the treatment of cancer, immunological diseases, inflammatory diseases, and neurological diseases.
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公开(公告)号：US12077515B2
公开(公告)日：2024-09-03
申请号：US17851882
申请日：2022-06-28
Applicant: Shuttle Pharmaceuticals, Inc.
Inventor： Scott Grindrod , Mira Jung , Anatoly Dritschilo
IPC: C07D285/135 , C07C237/20 , A61K45/06
CPC classification number: C07D285/135 , C07C237/20 , A61K45/06
Abstract: Selective HDAC inhibitors, and pharmaceutical compositions that include the same, are described herein for the treatment of cancer, immunological diseases, inflammatory diseases, and neurological diseases.
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公开(公告)号：US20230302034A1
公开(公告)日：2023-09-28
申请号：US18194648
申请日：2023-04-02
Applicant: Shuttle Pharmaceuticals, Inc.
Inventor： Scott Grindrod , Mira Jung , Olga Timofeeva , Milton Brown , Anatoly Dritschilo
IPC: A61K31/7072 , A61K33/243 , A61K31/513
CPC classification number: A61K31/7072 , A61K31/513 , A61K33/243 , A61K2121/00
Abstract: Methods and formulations are provided for treating cancer and neoplastic diseases in conjunction with radiation therapy where such methods and formulations include a combination of a radiosensitizing agent that is metabolized by thymidine phosphorylase and a thymidine phosphorylase inhibitor that increases the half-life of the radiosensitizing agent.
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公开(公告)号：US10745352B2
公开(公告)日：2020-08-18
申请号：US15555386
申请日：2016-03-03
Applicant: Shuttle Pharmaceuticals, Inc.
Inventor： Scott Grindrod , Mira Jung , Milton Brown , Anatoly Dritschilo
IPC: C07D403/14 , A61K31/404 , C07D209/42 , A61K31/573 , A61K45/06 , A61N5/00 , C07D209/20 , A61N5/10
Abstract: Dual function compounds are provided that may be inhibitors of histone deacetylase (HDAC) and activators of ataxia telangiectasia mutated (ATM). Pharmaceutical compositions and methods of use are also provided that utilize such compounds.
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Patent Agency Ranking
公开(公告)号：US20210078963A1
公开(公告)日：2021-03-18
申请号：US16959570
申请日：2019-01-08
Applicant: Shuttle Pharmaceuticals, Inc.
Inventor： Scott Grindrod , Mira Jung , Anatoly Dritschilo
IPC: C07D285/135 , C07C237/20
Abstract: Selective HDAC inhibitors, and pharmaceutical compositions that include the same, are described herein for the treatment of cancer, immunological diseases, inflammatory diseases, and neurological diseases.
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公开(公告)号：US10730834B2
公开(公告)日：2020-08-04
申请号：US15804746
申请日：2017-11-06
Applicant: Shuttle Pharmaceuticals, Inc.
Inventor： Scott Grindrod , Mira Jung , Milton Brown , Anatoly Dritschilo
IPC: C07D209/42 , A61K31/573 , A61K31/404 , A61K45/06 , A61N5/00 , C07D209/20 , C07D403/14 , A61N5/10
Abstract: Dual function compounds are provided that may be inhibitors of histone deacetylase (HDAC) and activators of ataxia telangiectasia mutated (ATM). Pharmaceutical compositions and methods of use are also provided that utilize such compounds.
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公开(公告)号：US11584733B2
公开(公告)日：2023-02-21
申请号：US17315567
申请日：2021-05-10
Applicant: Shuttle Pharmaceuticals, Inc.
Inventor： Scott Grindrod , Mira Jung , Milton Brown , Anatoly Dritschilo
IPC: C07D401/04 , A61P35/00 , C07D211/88 , A61K45/06
Abstract: Selective HDAC inhibitors, and pharmaceutical compositions that include the same, are described herein for the treatment of cancer, immunological diseases, inflammatory diseases, and neurological diseases.
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公开(公告)号：US20220348551A9
公开(公告)日：2022-11-03
申请号：US17315567
申请日：2021-05-10
Applicant: Shuttle Pharmaceuticals, Inc.
Inventor： Scott Grindrod , Mira Jung , Milton Brown , Anatoly Dritschilo
IPC: C07D401/04 , A61P35/00 , C07D211/88
Abstract: Selective HDAC inhibitors, and pharmaceutical compositions that include the same, are described herein for the treatment of cancer, immunological diseases, inflammatory diseases, and neurological diseases.
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公开(公告)号：US11407723B2
公开(公告)日：2022-08-09
申请号：US16959570
申请日：2019-01-08
Applicant: Shuttle Pharmaceuticals, Inc.
Inventor： Scott Grindrod , Mira Jung , Anatoly Dritschilo
IPC: C07D285/135 , C07C237/20 , A61K45/06
Abstract: Selective HDAC inhibitors, and pharmaceutical compositions that include the same, are described herein for the treatment of cancer, immunological diseases, inflammatory diseases, and neurological diseases.
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