专利检索 ap:("Silvano FUMERO" OR "Francesco PILATO" OR "Domenico BARONE" OR "Luisa BERTARIONE RAVA ROSSA" OR "Valentina MAINERO" OR "Silvio TRAVERSA") AND inv:"Francesco PILATO" 第 1 页

1.

发明申请
Use of K-252a and Kinase Inhibitors for the Prevention or Treatment of HMGB1-Associated Pathologies 审中-公开
标题翻译：使用K-252a和激酶抑制剂预防或治疗HMGB1相关病理

公开(公告)号：US20090191253A2

公开(公告)日：2009-07-30

申请号：US11658701

申请日：2007-01-29

申请人： Silvano FUMERO , Francesco PILATO , Domenico BARONE , Luisa BERTARIONE RAVA ROSSA , Valentina MAINERO , Silvio TRAVERSA

发明人： Silvano FUMERO , Francesco PILATO , Domenico BARONE , Luisa BERTARIONE RAVA ROSSA , Valentina MAINERO , Silvio TRAVERSA

IPC分类号： A61F2/04 , A61K31/407 , A61P37/02 , A61P9/00 , A61K39/395 , A61K31/7105 , A61K38/02 , A61K31/713

CPC分类号： A61K31/553 , A61K45/06 , A61K2300/00

摘要： The present invention relates to the use of K-252a, a physiologically active substance produced by microorganisms, and of its salts or synthetic and/or chemically modified derivatives for the prevention or treatment of HMGB1 associated pathologies. More particularly, the present invention relates to the use of K-252a for the prevention or treatment of restenosis.

摘要翻译： 本发明涉及由微生物产生的生理活性物质及其盐或合成和/或化学修饰的衍生物K-252a用于预防或治疗HMGB1相关病理学的用途。更具体地，本发明涉及K-252a用于预防或治疗再狭窄的用途。