公开(公告)号：US09770521B2

公开(公告)日：2017-09-26

申请号：US14398871

申请日：2013-05-08

Applicant: Sinvent AS

Inventor： Tormod Selbekk ,  Geirmund Unsgård

IPC: A61K49/22 ,  A61B8/08

CPC classification number: A61K49/22 ,  A61B8/0808 ,  A61K49/226

Abstract: An aqueous ultrasound contact fluid includes a pharmaceutical grade triglyceride and a pharmaceutically acceptable emulsifier and the use of the ultrasound contact fluid in an intraoperative or interventional ultrasound imaging procedure. A method for intraoperative ultrasound imaging includes filling an aqueous ultrasound contact fluid into a body cavity. The aqueous ultrasound contact fluid is a composition comprising a pharmaceutical grade triglyceride and a pharmaceutically acceptable emulsifier and optionally a pharmaceutically acceptable humectant, and the triglyceride content is in the range of 8-240 g/1000 ml composition contact fluid and the amount of emulsifier is 0.4-18 g/1000 ml composition contact fluid, and optionally a humectant in the amount of 1.2-30 g/1000 ml. The method further includes obtaining an ultrasound image of a body region that comprises at least part of the body cavity filled with the aqueous ultrasound contact fluid. The aqueous ultrasound contact fluid reduces image artifacts associated with the body cavity.

公开(公告)号：US20150118161A1

公开(公告)日：2015-04-30

申请号：US14398871

申请日：2013-05-08

Applicant: Sinvent AS

Inventor： Tormod Selbekk ,  Geirmund Unsgård

IPC: A61K49/22

CPC classification number: A61K49/22 ,  A61B8/0808 ,  A61K49/226

Abstract: The present invention concerns an aqueous ultrasound contact fluid comprising a pharmaceutical grade triglyceride and a pharmaceutically acceptable emulsifier and the use of said ultrasound contact fluid in an intraoperative or interventional ultrasound imaging procedure.

Abstract translation: 本发明涉及包含药物级甘油三酯和药学上可接受的乳化剂的水性超声接触流体，以及在术中或介入超声成像程序中使用所述超声接触流体。