保存成功
保存失败
公开(公告)号:US20040171117A1
公开(公告)日:2004-09-02
申请号:US10738809
申请日:2003-12-17
申请人: SmithKline Beecham Corporation , SmithKline Beecham p.l.c.
发明人: Mark A. Tornetta , Raymond W. Sweet , Alemseged Truneh , Trevor A. Wattam
IPC分类号: A61K039/395 , C07H021/04 , C07K016/28 , C12N005/06
CPC分类号: C07K16/2875 , A61K2039/505 , C07K2317/56 , C07K2317/565
摘要: Chimeric, humanized and other RANK-L MAbs, derived from high affinity neutralizing MAbs, pharmaceutical compositions containing same, methods of treatment and diagnostics are provided.
摘要翻译: 提供衍生自高亲和力中和MAB的嵌合,人源化和其它RANK-L MAb,含有其的药物组合物,治疗方法和诊断。