公开(公告)号：US20040209822A1

公开(公告)日：2004-10-21

申请号：US10844699

申请日：2004-05-13

Applicant: SmithKline Beecham p.l.c.

Inventor： Andrew Faller ,  Anne-Geraldine Rousseau ,  David Timothy MacPherson ,  Peter Henry Milner

IPC: A61K038/04 ,  C07F005/00

CPC classification number: C07C311/13 ,  C07C259/06 ,  C07D307/52

Abstract: Compounds of the formula (I): 1 wherein: X1 is alkyl, sulphonyl or carboxy; X2 is hydrogen or alkyl; R1 is arylmethyl or heterocycylmethyl; R2 is alkyl, alkenyl, cycloalkyl or cycloalkenyl; and R3 is hydrogen, alkyl, alkenyl, alkynyl or aryl; are useful in the treatment of disorders mediated by s-CD23.

Abstract translation: 式（I）的化合物：其中：X 1是烷基，磺酰基或羧基; X 2是氢或烷基; R 1是芳基甲基或杂环基甲基; R 2是烷基，烯基，环烷基或环烯基; 和R 3是氢，烷基，烯基，炔基或芳基; 可用于治疗由s-CD23介导的疾病。