公开(公告)号：US20030073645A1

公开(公告)日：2003-04-17

申请号：US10290132

申请日：2002-11-07

Applicant: SmithKline Beecham plc

Inventor： Stephen Alistair Smith

IPC: A61K031/70 ,  A61K031/4439

CPC classification number: A61K31/702 ,  A61K31/44 ,  A61K31/445 ,  A61K45/06 ,  A61K2300/00

Abstract: A method for the treatment of diabetes mellitus and conditions associated with diabetes mellitus in a mammal, which method comprises administering an effective non-toxic and pharmaceutically acceptable amount of an insulin sensitiser and an alpha-glucosidase inhibitor antihyperglycaemic agent, to a mammal in need thereof.

Abstract translation: 一种用于治疗哺乳动物的糖尿病和与糖尿病有关的病症的方法，所述方法包括向有需要的哺乳动物施用有效的无毒和药学上可接受量的胰岛素敏化剂和α-葡糖苷酶抑制剂抗高血糖药物 。

公开(公告)号：US20020137772A1

公开(公告)日：2002-09-26

申请号：US10099161

申请日：2002-03-13

Applicant: SmithKline Beecham plc

Inventor： Stephen Alistair Smith

IPC: A61K031/4439 ,  A61K031/155

CPC classification number: A61K31/44 ,  A61K2300/00

Abstract: A method for the treatment and/or prophylaxis of diabetes mellitus, conditions associated with diabetes mellitus and certain complications thereof, in a mammal which method comprises administering an effective non-toxic and pharmaceutically acceptable amount of an insulin sensitiser and a biguanidine antihyperglycaemic agent, to a mammal in need thereof and a pharmaceutical composition comprising an insulin sensitiser and a biguanide antihyperglycaemic agent.

Abstract translation: 一种用于治疗和/或预防糖尿病的方法，与糖尿病有关的病症及其某些并发症的方法，所述方法包括给予有效的无毒和药学上可接受量的胰岛素敏化剂和双胍类抗高血糖药， 需要其的哺乳动物和包含胰岛素敏化剂和双胍抗高血糖药的药物组合物。

公开(公告)号：US20020123514A1

公开(公告)日：2002-09-05

申请号：US10091008

申请日：2002-03-05

Applicant: SmithKline Beecham plc

Inventor： Stephen Alistair Smith

IPC: A61K031/4439

CPC classification number: A61K31/702 ,  A61K31/44 ,  A61K31/445 ,  A61K45/06 ,  A61K2300/00

Abstract: A method for the treatment of diabetes mellitus and conditions associated with diabetes mellitus in a mammal, which method comprises administering an effective non-toxic and pharmaceutically acceptable amount of an insulin sensitizer and an alpha-glucosidase inhibitor antihyperglycaemic agent, to a mammal in need thereof.

Abstract translation: 一种用于治疗哺乳动物的糖尿病和与糖尿病有关的病症的方法，该方法包括向有需要的哺乳动物施用有效的无毒和可药用量的胰岛素敏化剂和α-葡糖苷酶抑制剂抗高血糖药物 。

公开(公告)号：US20020052324A1

公开(公告)日：2002-05-02

申请号：US09989572

申请日：2001-11-20

Applicant: SmithKline Beecham plc

Inventor： Robin Edwin Buckingham ,  Stephen Alistair Smith

IPC: A61K031/70 ,  A61K031/426

CPC classification number: A61K31/702 ,  A61K31/64 ,  A61K45/06 ,  A61K2300/00

Abstract: A method for the treatment of diabetes mellitus and conditions associated with diabetes mellitus in a mammal, which method comprises administering an effective non-toxic and pharmaceutically acceptable amount of an insulin sensitizer, an insulin secretagogue and an alpha glucosidase inhibitor antihyperglycaemic agent, to a mammal in need thereof; and composition for use in such method.

Abstract translation: 一种用于治疗哺乳动物的糖尿病和与糖尿病有关的病症的方法，所述方法包括向哺乳动物施用有效的无毒和药学上可接受量的胰岛素敏化剂，胰岛素促分泌素和α葡糖苷酶抑制剂抗高血糖药物 有需要的 和用于该方法的组合物。

公开(公告)号：US20030109553A1

公开(公告)日：2003-06-12

申请号：US10340426

申请日：2003-01-10

Applicant: SmithKline Beecham plc

Inventor： Stephen Alistair Smith

IPC: A61K031/4439 ,  A61K031/426 ,  A61K031/155

CPC classification number: A61K31/44 ,  A61K2300/00

Abstract: A method for the treatment and/or prophylaxis of diabetes mellitus, conditions associated with diabetes mellitus and certain complications thereof, in a mammal which method comprises administering an effective non-toxic and pharmaceutically acceptable amount of an insulin sensitiser and a biguanide antihyperglycaemic agent, to a mammal in need thereof and a pharmaceutical composition comprising an insulin sensitiser and a biguanide antihyperglycaemic agent.

Abstract translation: 一种用于治疗和/或预防糖尿病的方法，与糖尿病有关的病症及其某些并发症的方法，所述方法包括向所述哺乳动物施用有效的无毒和药学上可接受量的胰岛素敏化剂和双胍类抗高血糖药， 需要其的哺乳动物和包含胰岛素敏化剂和双胍抗高血糖药的药物组合物。