公开(公告)号：US20230357113A1

公开(公告)日：2023-11-09

申请号：US18144297

申请日：2023-05-08

Applicant: Sol-Gel Technologies Ltd.

Inventor： Moshe Arkin ,  Natalie Utsis ,  Ariel Mitelman ,  Bar Havazelt ,  Shai Dan

IPC: C07C37/84

CPC classification number: C07C37/84 ,  C07B2200/13

Abstract: The present invention relates to crystalline polymorphs of Tapinarof, e.g., Tapinarof crystalline Form B, Form C, and Form D, pharmaceutical compositions comprising the same, processes for preparation thereof, and uses thereof for treatment of skin disorders.