公开(公告)号：US5849961A

公开(公告)日：1998-12-15

申请号：US812543

申请日：1997-03-07

申请人： Sotaro Miyano ,  Kenta Sakurai ,  Nobuyuki Koike ,  Tetsutaro Hattori

发明人： Sotaro Miyano ,  Kenta Sakurai ,  Nobuyuki Koike ,  Tetsutaro Hattori

IPC分类号： C07B57/00 ,  C07C39/12 ,  C07C35/42

CPC分类号： C07C39/12 ,  C07B57/00 ,  C07C2103/26

摘要： The novel optically active 1,1'-biphenanthryl-2,2'-diol is disclosed, which is obtained by preparing N((S)-1-phenylethyl)-1,1'-biphenanthryl-2,2'-diylthiophosphorylamide by using optically active phenylethylamine, recrystallizing the compound into an optically active compound, followed by reduction with a reducing agent. The diol compound according to the present invention is useful as a resolving reagent, a starting material of an optically active phosphine compound or a ligand in asymmetric synthesis, forming a complex with a transition metal or a rare earth element to provide a useful catalyst.

摘要翻译： 公开了通过制备N（（S）-1-苯基乙基）-1,1'-联苯-2,2'-二基硫代磷酰胺得到的新型光学活性1,1'-联蒽醌-2,2'-二醇 使用光学活性苯乙胺，将化合物重结晶为光学活性化合物，然后用还原剂还原。 根据本发明的二醇化合物可用作拆分试剂，光学活性膦化合物的原料或不对称合成中的配体，与过渡金属或稀土元素形成络合物以提供有用的催化剂。