专利检索 ap:("Southern Research Institute" OR "The University of North Carolina at Chapel Hill" OR "Vanderbilt University") AND inv:"John Phillip Tillotson" 第 1 页

1.

发明授权
Substituted phenyl ethynyl pyridine carboxamides as potent inhibitors of SARS virus 有权

公开(公告)号：US11905306B2

公开(公告)日：2024-02-20

申请号：US18086445

申请日：2022-12-21

申请人： Southern Research Institute , The University of North Carolina at Chapel Hill , Vanderbilt University

发明人： Syed Kaleem Ahmed , Shilpa Dutta , John Phillip Tillotson , Corinne E. Augelli-Szafran , Ashish Kumar Pathak , Omar Moukha-Chafiq , Timothy Patrick Sheahan , Ralph S. Baric , Amy Catherine Sims , Mark R. Denison

IPC分类号： C07F9/58 , C07D213/56 , C07D401/12 , C07D413/12 , C07D417/12

CPC分类号： C07F9/58 , C07D213/56 , C07D401/12 , C07D413/12 , C07D417/12

摘要： The present disclosure is concerned with substituted phenyl ethynyl pyridine carboxamide compounds, pharmaceutical compositions comprising the compounds, and methods of treating viral infections due to a Coronavirus such as, for example, Middle East respiratory syndrome coronavirus (MERS-CoV), severe acute respiratory syndrome coronavirus (SARS-CoV), and severe acute respiratory syndrome coronavirus disease 2019 (SARS-CoV-2), using the compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

2.

发明公开
SUBSTITUTED PHENYL ET458HYNYL PYRIDINE CARBOXAMIDES AS POTENT INHIBITORS OF SARS VIRUS 审中-公开

公开(公告)号：US20230192733A1

公开(公告)日：2023-06-22

申请号：US18086445

申请日：2022-12-21

申请人： Southern Research Institute , The University of North Carolina at Chapel Hill , Vanderbilt University

发明人： Syed Kaleem Ahmed , Shilpa Dutta , John Phillip Tillotson , Corinne E. Augelli-Szafran , Ashish Kumar Pathak , Omar Moukha-Chafiq , Timothy Patrick Sheahan , Ralph S. Baric , Amy Catherine Sims , Mark R. Denison

IPC分类号： C07F9/58 , C07D213/56 , C07D413/12 , C07D401/12 , C07D417/12

CPC分类号： C07F9/58 , C07D213/56 , C07D413/12 , C07D401/12 , C07D417/12

摘要： The present disclosure is concerned with substituted phenyl ethynyl pyridine carboxamide compounds, pharmaceutical compositions comprising the compounds, and methods of treating viral infections due to a Coronavirus such as, for example, Middle East respiratory syndrome coronavirus (MERS-CoV), severe acute respiratory syndrome coronavirus (SARS-CoV), and severe acute respiratory syndrome coronavirus disease 2019 (SARS-CoV-2), using the compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.