公开(公告)号：US07371744B2

公开(公告)日：2008-05-13

申请号：US10723420

申请日：2003-11-26

申请人： Stanley B. Brown ,  Cassandra C. O'Grady ,  John Griffiths ,  Kirste J. Mellish ,  David I. Vernon

发明人： Stanley B. Brown ,  Cassandra C. O'Grady ,  John Griffiths ,  Kirste J. Mellish ,  David I. Vernon

IPC分类号： A61K31/54

CPC分类号： A61K49/003 ,  A61K8/4986 ,  A61K41/0057 ,  A61L2/0029 ,  A61L2/0082 ,  A61L2/08 ,  A61L2/232 ,  A61Q11/00 ,  C07D279/18

摘要： A phenothiazinium compound of Formula (I): wherein: A and B each independently is in which R′ and R″ each independently is a linear, branched or cyclic hydrocarbon group, or R′ and R″ together with the N atom to which they are attached form an optionally substituted 5-, 6- or 7-membered ring; and where XP− is a counteranion and P is 1, 2 or 3; except for the compounds in which A and B are both either —N(CH3)2 or —N(CH2CH3)2 for use in a treatment that requires removal, deactivation or killing of unwanted tissues or cells.

摘要翻译： 式（I）的吩噻嗪鎓化合物：其中：A和B各自独立地是其中R'和R“各自独立地是直链，支链或环状烃基，或者R'和R”连同N原子与 它们连接形成任选取代的5-，6-或7-元环; 并且其中P 是抗衡阴离子，P是1,2或3; 除了其中A和B均为-N（CH 3）2 - 或-N（CH 2 CH 2） 3 ，用于需要去除，失活或杀死不想要的组织或细胞的治疗。