专利检索 ap:("Stephen Benkovic" OR "Lucy Shapiro" OR "Rachel Wright" OR "Craig Stephens" OR "Lyn Kahng" OR "Anthony Berdis" OR "Irene Lee") AND inv:"Lyn Kahng" 第 1 页

1.

发明申请
Treatment of bacterial induced diseases using DNA methyl transferase inhibitors 审中-公开
标题翻译：使用DNA甲基转移酶抑制剂治疗细菌诱导的疾病

公开(公告)号：US20050227933A1

公开(公告)日：2005-10-13

申请号：US10615703

申请日：2003-07-09

申请人： Stephen Benkovic , Lucy Shapiro , Rachel Wright , Craig Stephens , Lyn Kahng , Anthony Berdis , Irene Lee

发明人： Stephen Benkovic , Lucy Shapiro , Rachel Wright , Craig Stephens , Lyn Kahng , Anthony Berdis , Irene Lee

IPC分类号： A61K48/00 , C07F5/02

CPC分类号： C07F5/025

摘要： Methods for treating and/or preventing disease conditions caused or induced or aggravated by microbes, especially bacteria, by inhibiting DNA methyltransferase activity, such as by administering to an animal a DNA methyltransferase inhibitor, are disclosed, along with methods of reducing or ablating virulence in bacteria by inhibiting DNA methyltransferase activity.

摘要翻译： 通过抑制DNA甲基转移酶活性，例如通过向动物施用DNA甲基转移酶抑制剂来治疗和/或预防由微生物，特别是细菌引起或加剧的疾病状况的方法，以及降低或消除毒性的方法细菌通过抑制DNA甲基转移酶活性。