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公开(公告)号:US07943749B2
公开(公告)日:2011-05-17
申请号:US11740998
申请日:2007-04-27
申请人: Stephen Hanessian , Janek Szychowski , Susanta Sekhar Adhikari , Kandasamy Pachamuthu , Michael T. Migawa , Richard H. Griffey , Eric Swayze
发明人: Stephen Hanessian , Janek Szychowski , Susanta Sekhar Adhikari , Kandasamy Pachamuthu , Michael T. Migawa , Richard H. Griffey , Eric Swayze
CPC分类号: C07H15/232
摘要: The present invention is directed to analogs of paromomycin having a variety of chemical functional groups attached at the 2″-O-position as well as their preparation and use as prophylactic or therapeutics against microbial infection.
摘要翻译: 本发明涉及具有连接在2“-O-位上的各种化学官能团的巴龙霉素类似物及其制备和用作抗微生物感染的预防或治疗剂。
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2.ANTIBACTERIAL 4,5-SUBSTITUTED AMINOGLYCOSIDE ANALOGS HAVING MULTIPLE SUBSTITUENTS 有权
标题翻译: 具有多种替代物的抗体4,5-取代的氨基酰胺类似物公开(公告)号:US20080293649A1
公开(公告)日:2008-11-27
申请号:US12130048
申请日:2008-05-30
申请人: Eric E. Swayze , Stephen Hanessian , Janek Szychowski , Susanta Sekhar Adhikari , Kandasamy Pachamuthu , Xiaojing Wang , Michael T. Migawa , Richard H. Griffey
发明人: Eric E. Swayze , Stephen Hanessian , Janek Szychowski , Susanta Sekhar Adhikari , Kandasamy Pachamuthu , Xiaojing Wang , Michael T. Migawa , Richard H. Griffey
IPC分类号: A61K31/7036 , C07H15/232 , A61P31/04
CPC分类号: C07H15/23 , C07H15/232
摘要: The present invention is directed to analogs of aminoglycoside compounds as well as their preparation and use as prophylactic or therapeutics against microbial infection.
摘要翻译: 本发明涉及氨基糖苷类化合物的类似物以及它们作为抗微生物感染的预防或治疗剂的制备和用途。
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3.Antibacterial 4,5-substituted aminoglycoside analogs having multiple substituents 有权
标题翻译: 具有多个取代基的抗菌的4,5-取代的氨基糖苷类似物公开(公告)号:US08569264B2
公开(公告)日:2013-10-29
申请号:US13344247
申请日:2012-01-05
申请人: Eric E. Swayze , Stephen Hanessian , Janek Szychowski , Susanta Sekhar Adhikari , Kandasamy Pachamuthu , Xiaojing Wang , Michael T. Migawa , Richard H. Griffey
发明人: Eric E. Swayze , Stephen Hanessian , Janek Szychowski , Susanta Sekhar Adhikari , Kandasamy Pachamuthu , Xiaojing Wang , Michael T. Migawa , Richard H. Griffey
IPC分类号: A01N43/04 , A61K31/715
CPC分类号: C07H15/23 , C07H15/232
摘要: The present invention is directed to analogs of aminoglycoside compounds as well as their preparation and use as prophylactic or therapeutics against microbial infection.
摘要翻译: 本发明涉及氨基糖苷类化合物的类似物以及它们作为抗微生物感染的预防或治疗剂的制备和用途。
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4.Antibacterial 4,5-substituted aminoglycoside analogs having multiple substituents 有权
标题翻译: 具有多个取代基的抗菌的4,5-取代的氨基糖苷类似物公开(公告)号:US08114856B2
公开(公告)日:2012-02-14
申请号:US12987842
申请日:2011-01-10
申请人: Eric E. Swayze , Stephen Hanessian , Janek Szychowski , Susanta Sekhar Adhikari , Kandasamy Pachamuthu , Xiaojing Wang , Michael T. Migawa , Richard H. Griffey
发明人: Eric E. Swayze , Stephen Hanessian , Janek Szychowski , Susanta Sekhar Adhikari , Kandasamy Pachamuthu , Xiaojing Wang , Michael T. Migawa , Richard H. Griffey
IPC分类号: A01N43/04 , A61K31/715
CPC分类号: C07H15/23 , C07H15/232
摘要: The present invention is directed to analogs of aminoglycoside compounds as well as their preparation and use as prophylactic or therapeutics against microbial infection.
摘要翻译: 本发明涉及氨基糖苷类化合物的类似物以及它们作为抗微生物感染的预防或治疗剂的制备和用途。
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5.ANTIBACTERIAL 4,5-SUBSTITUTED AMINOGLYCOSIDE ANALOGS HAVING MULTIPLE SUBSTITUENTS 有权
标题翻译: 具有多种替代物的抗体4,5-取代的氨基酰胺类似物公开(公告)号:US20110166334A1
公开(公告)日:2011-07-07
申请号:US12987842
申请日:2011-01-10
申请人: Eric E. Swayze , Stephen Hanessian , Janek Szychowski , Susanta Sekhar Adhikari , Kandasamy Pachamuthu , Xiaojing Wang , Michael T. Migawa , Richard H. Griffey
发明人: Eric E. Swayze , Stephen Hanessian , Janek Szychowski , Susanta Sekhar Adhikari , Kandasamy Pachamuthu , Xiaojing Wang , Michael T. Migawa , Richard H. Griffey
IPC分类号: C07J41/00 , C07H15/232
CPC分类号: C07H15/23 , C07H15/232
摘要: The present invention is directed to analogs of aminoglycoside compounds as well as their preparation and use as prophylactic or therapeutics against microbial infection.
摘要翻译: 本发明涉及氨基糖苷类化合物的类似物以及它们作为预防或治疗微生物感染的制备和用途。
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6.ANTIBACTERIAL 4,5-SUBSTITUTED AMINOGLYCOSIDE ANALOGS HAVING MULTIPLE SUBSTITUENTS 有权
标题翻译: 具有多种替代物的抗体4,5-取代的氨基酰胺类似物公开(公告)号:US20130005674A1
公开(公告)日:2013-01-03
申请号:US13344247
申请日:2012-01-05
申请人: Eric E. Swayze , Stephen Hanessian , Janek Szychowski , Susanta Sekhar Adhikari , Kandasamy Pachamuthu , Xiaojing Wang , Michael T. Migawa , Richard H. Griffey
发明人: Eric E. Swayze , Stephen Hanessian , Janek Szychowski , Susanta Sekhar Adhikari , Kandasamy Pachamuthu , Xiaojing Wang , Michael T. Migawa , Richard H. Griffey
IPC分类号: A61K31/7036 , A61P31/04
CPC分类号: C07H15/23 , C07H15/232
摘要: The present invention is directed to analogs of aminoglycoside compounds as well as their preparation and use as prophylactic or therapeutics against microbial infection.
摘要翻译: 本发明涉及氨基糖苷类化合物的类似物以及它们作为抗微生物感染的预防或治疗剂的制备和用途。
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7.Antibacterial 4,5-substituted aminoglycoside analogs having multiple substituents 有权
标题翻译: 具有多个取代基的抗菌的4,5-取代的氨基糖苷类似物公开(公告)号:US07893039B2
公开(公告)日:2011-02-22
申请号:US12130048
申请日:2008-05-30
申请人: Eric E. Swayze , Stephen Hanessian , Janek Szychowski , Susanta Sekhar Adhikari , Kandasamy Pachamuthu , Xiaojing Wang , Michael T. Migawa , Richard H. Griffey
发明人: Eric E. Swayze , Stephen Hanessian , Janek Szychowski , Susanta Sekhar Adhikari , Kandasamy Pachamuthu , Xiaojing Wang , Michael T. Migawa , Richard H. Griffey
IPC分类号: A01N43/04 , A61K31/715
CPC分类号: C07H15/23 , C07H15/232
摘要: The present invention is directed to analogs of aminoglycoside compounds as well as their preparation and use as prophylactic or therapeutics against microbial infection.
摘要翻译: 本发明涉及氨基糖苷类化合物的类似物以及它们作为抗微生物感染的预防或治疗剂的制备和用途。
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公开(公告)号:US20080045468A1
公开(公告)日:2008-02-21
申请号:US11740998
申请日:2007-04-27
申请人: Stephen Hanessian , Janek Szychowski , Susanta Adhikari , Kandasamy Pachamuthu , Michael Migawa , Richard Griffey , Eric Swayze
发明人: Stephen Hanessian , Janek Szychowski , Susanta Adhikari , Kandasamy Pachamuthu , Michael Migawa , Richard Griffey , Eric Swayze
IPC分类号: A61K31/7036 , A61P31/04 , C07H15/232
CPC分类号: C07H15/232
摘要: The present invention is directed to analogs of paromomycin having a variety of chemical functional groups attached at the 2″-O-position as well as their preparation and use as prophylactic or therapeutics against microbial infection.
摘要翻译: 本发明涉及具有连接在2'-O-位上的各种化学官能团的巴龙霉素的类似物以及它们作为抗微生物感染的预防或治疗剂的制备和用途。
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