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公开(公告)号：US20070128210A1
公开(公告)日：2007-06-07
申请号：US11592128
申请日：2006-11-03
CPC分类号： C07K14/315
摘要： β-hemolytic streptococci polynucleotides, polypeptides, particularly Streptococcus pyogenes polypeptides and polynucleotides, and antibodies of these polypeptides are described. The polynucleotides, polypeptides, and antibodies of the invention can be formulated for use as immunogenic compositions. Also disclosed are methods for immunizing against and reducing β-hemolytic streptococcal infection, and for detecting β-hemolytic streptococci in a biological sample.
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公开(公告)号：US20070128229A1
公开(公告)日：2007-06-07
申请号：US11592200
申请日：2006-11-03
IPC分类号： A61K39/09 , C07H21/04 , C07K14/315 , C12N1/21
CPC分类号： C07K14/315 , A61K39/00 , A61K39/09
摘要： β-hemolytic streptococci polynucleotides, polypeptides, particularly Streptococcus pyogenes polypeptides and polynucleotides, and antibodies of these polypeptides are described. The polynucleotides, polypeptides, and antibodies of the invention can be formulated for use as immunogenic compositions. Also disclosed are methods for immunizing against and reducing β-hemolytic streptococcal infection, and for detecting β-hemolytic streptococci in a biological sample.
摘要翻译： 描述了β-溶血性链球菌多核苷酸，多肽，特别是化脓性链球菌多肽和多核苷酸，以及这些多肽的抗体。 本发明的多核苷酸，多肽和抗体可配制成用作免疫原性组合物。 还公开了用于免疫抗原和减少β-溶血性链球菌感染以及用于检测生物样品中的β-溶血性链球菌的方法。
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公开(公告)号：US20070128211A1
公开(公告)日：2007-06-07
申请号：US11592153
申请日：2006-11-03
CPC分类号： C07K14/315
摘要： β-hemolytic streptococci polynucleotides, polypeptides, particularly Streptococcus pyogenes polypeptides and polynucleotides, and antibodies of these polypeptides are described. The polynucleotides, polypeptides, and antibodies of the invention can be formulated for use as immunogenic compositions. Also disclosed are methods for immunizing against and reducing β-hemolytic streptococcal infection, and for detecting β-hemolytic streptococci in a biological sample.
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4.发明申请Recombinant expression of streptococcus pyogenes cysteine protease and immunogenic compositions thereof 审中-公开化脓性链球菌半胱氨酸蛋白酶的重组表达及其免疫原性组成公开(公告)号：US20060189791A1
公开(公告)日：2006-08-24
申请号：US10564264
申请日：2004-07-07
IPC分类号： C07K14/315 , C07H21/04 , C12P21/06 , C12N1/21 , C12N15/74
CPC分类号： C07K14/315 , A61K39/00 , C07K16/40 , C12N9/52
摘要： The present invention generally relates to the fields of molecular biology, clinical bacteriology and protein folding. More particularly, the invention relates to methods for recombinantly expressing a soluble mature Streptococcus pyogenesexotoxin B (SpeB) polypeptide in a host cell.
摘要翻译： 本发明一般涉及分子生物学，临床细菌学和蛋白质折叠领域。 更具体地说，本发明涉及在宿主细胞中重组表达可溶性成熟的脓性链球菌脓毒素B（SpeB）多肽的方法。
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