Crystalline forms of a factor Xa inhibitor
    3.
    发明申请
    Crystalline forms of a factor Xa inhibitor 有权
    晶体形式的因子Xa抑制剂

    公开(公告)号:US20060148846A1

    公开(公告)日:2006-07-06

    申请号:US11302692

    申请日:2005-12-14

    IPC分类号: C07D471/02 A61K31/4745

    CPC分类号: C07D471/04

    摘要: The instant invention provides crystalline forms of 3-(1-hydroxy-1-methyl-ethyl)-1-(4-methoxy-phenyl)-6-[4-(2-oxo-2H-pyridin-1-yl)-phenyl]-1,4,5,6-tetrahydro-pyrazolo[3,4-c]pyridin-7-one and its solvates thereof; processes for the production of such crystalline forms; pharmaceutical compositions comprising such crystalline forms; and methods of treating thromboembolic disorders with such crystalline forms or such pharmaceutical compositions.

    摘要翻译: 本发明提供3-(1-羟基-1-甲基 - 乙基)-1-(4-甲氧基 - 苯基)-6- [4-(2-氧代-2H-吡啶-1-基) - 苯基] -1,4,5,6-四氢 - 吡唑并[3,4-c]吡啶-7-酮及其溶剂合物; 生产这种结晶形式的方法; 包含这种结晶形式的药物组合物; 以及用这种结晶形式或这种药物组合物治疗血栓栓塞障碍的方法。