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1.发明授权Semi-solid delivery vehicle and pharmaceutical compositions for delivery of granisetron 有权半固体输送载体和用于输送格拉司琼的药物组合物公开(公告)号：US08252304B2
公开(公告)日：2012-08-28
申请号：US12564881
申请日：2009-09-22
申请人： Steven Y. Ng , Hui Rong Shen , Jorge Heller
发明人： Steven Y. Ng , Hui Rong Shen , Jorge Heller
IPC分类号： A61K31/435 , A61K31/439 , A61K31/53 , A61K47/30 , C07D319/04
CPC分类号： A61K47/34 , A61K8/85 , A61K8/86 , A61K9/0014 , A61K9/0019 , A61K9/0024 , A61K9/06 , A61K9/1647 , A61K31/439 , A61K31/445 , A61K31/573 , A61K31/765 , A61K45/06 , A61K47/10 , A61Q15/00 , A61Q17/04 , A61Q19/00
摘要： A semi-solid delivery vehicle contains a polyorthoester and an excipient, and a semi-solid pharmaceutical composition contains an active agent and the delivery vehicle. The pharmaceutical composition may be a topical, syringable, or injectable formulation; and is suitable for local delivery of the active agent. Methods of treatment are also disclosed.
摘要翻译： 半固体递送载体含有聚原酸酯和赋形剂，半固体药物组合物含有活性剂和递送载体。 药物组合物可以是局部，注射剂或可注射制剂; 并适用于活性剂的局部递送。 还公开了治疗方法。
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公开(公告)号：US20120283253A1
公开(公告)日：2012-11-08
申请号：US13552083
申请日：2012-07-18
申请人： Steven Y. NG , Hui-Rong Shen , Jorge Heller
发明人： Steven Y. NG , Hui-Rong Shen , Jorge Heller
CPC分类号： A61K47/34 , A61K8/85 , A61K8/86 , A61K9/0014 , A61K9/0019 , A61K9/0024 , A61K9/06 , A61K9/1647 , A61K31/439 , A61K31/445 , A61K31/573 , A61K31/765 , A61K45/06 , A61K47/10 , A61Q15/00 , A61Q17/04 , A61Q19/00
摘要： A semi-solid delivery vehicle contains a polyorthoester and an excipient, and a semi-solid pharmaceutical composition contains an active agent and the delivery vehicle. The pharmaceutical composition may be a topical, syringable, or injectable formulation; and is suitable for local delivery of the active agent. Methods of treatment are also disclosed.
摘要翻译： 半固体递送载体含有聚原酸酯和赋形剂，半固体药物组合物含有活性剂和递送载体。 药物组合物可以是局部，注射剂或可注射制剂; 并适用于活性剂的局部递送。 还公开了治疗方法。
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公开(公告)号：US06790458B2
公开(公告)日：2004-09-14
申请号：US10409408
申请日：2003-04-07
申请人： Steven Y. Ng , Hui-Rong Shen , Jorge Heller
发明人： Steven Y. Ng , Hui-Rong Shen , Jorge Heller
IPC分类号： A61K958
摘要： A semi-solid delivery vehicle contains a polyorthoester and an excipient, and a semi-solid pharmaceutical composition contains an active agent and the delivery vehicle. The pharmaceutical composition may be a topical, syringable, or injectable formulation; and is suitable for local delivery of the active agent. Methods of treatment are also disclosed.
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公开(公告)号：US06613355B2
公开(公告)日：2003-09-02
申请号：US09854180
申请日：2001-05-11
申请人： Steven Y. Ng , Hui-Rong Shen , Jorge Heller
发明人： Steven Y. Ng , Hui-Rong Shen , Jorge Heller
IPC分类号： A61K958
摘要： A semi-solid delivery vehicle contains a polyorthoester and an excipient, and a semi-solid pharmaceutical composition contains an active agent and the delivery vehicle. The pharmaceutical composition may be a topical, syringable, or injectable formulation; and is suitable for local delivery of the active agent. Methods of treatment are also disclosed.
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5.发明授权Methods of treating emesis utilizing semi-solid delivery pharmaceutical compositions comprising granisetron 有权使用包含格拉司琼的半固体递送药物组合物治疗呕吐的方法公开(公告)号：US08252305B2
公开(公告)日：2012-08-28
申请号：US13279938
申请日：2011-10-24
申请人： Steven Y. Ng , Hui Rong Shen , Jorge Heller
发明人： Steven Y. Ng , Hui Rong Shen , Jorge Heller
IPC分类号： A61K31/439 , A61K31/435 , A61K31/46 , A61K31/416 , A61K47/30 , A61P1/08 , C07D319/04
CPC分类号： A61K47/34 , A61K8/85 , A61K8/86 , A61K9/0014 , A61K9/0019 , A61K9/0024 , A61K9/06 , A61K9/1647 , A61K31/439 , A61K31/445 , A61K31/573 , A61K31/765 , A61K45/06 , A61K47/10 , A61Q15/00 , A61Q17/04 , A61Q19/00
摘要： A semi-solid delivery vehicle contains a polyorthoester and an excipient, and a semi-solid pharmaceutical composition contains an active agent and the delivery vehicle. The pharmaceutical composition may be a topical, syringable, or injectable formulation; and is suitable for local delivery of the active agent. Methods of treatment are also disclosed.
摘要翻译： 半固体递送载体含有聚原酸酯和赋形剂，半固体药物组合物含有活性剂和递送载体。 药物组合物可以是局部，注射剂或可注射制剂; 并适用于活性剂的局部递送。 还公开了治疗方法。
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公开(公告)号：US20120041020A1
公开(公告)日：2012-02-16
申请号：US13279938
申请日：2011-10-24
申请人： Steven Y. Ng , Hui Rong Shen , Jorge Heller
发明人： Steven Y. Ng , Hui Rong Shen , Jorge Heller
IPC分类号： A61K31/439 , A61P1/08 , A61K47/34
CPC分类号： A61K47/34 , A61K8/85 , A61K8/86 , A61K9/0014 , A61K9/0019 , A61K9/0024 , A61K9/06 , A61K9/1647 , A61K31/439 , A61K31/445 , A61K31/573 , A61K31/765 , A61K45/06 , A61K47/10 , A61Q15/00 , A61Q17/04 , A61Q19/00
摘要： A semi-solid delivery vehicle contains a polyorthoester and an excipient, and a semi-solid pharmaceutical composition contains an active agent and the delivery vehicle. The pharmaceutical composition may be a topical, syringable, or injectable formulation; and is suitable for local delivery of the active agent. Methods of treatment are also disclosed.
摘要翻译： 半固体递送载体含有聚原酸酯和赋形剂，半固体药物组合物含有活性剂和递送载体。 药物组合物可以是局部，注射剂或可注射制剂; 并适用于活性剂的局部递送。 还公开了治疗方法。
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7.发明授权Semi-solid delivery vehicle and pharmaceutical compositions for delivery of granisetron 有权半固体输送载体和用于输送格拉司琼的药物组合物公开(公告)号：US08715710B2
公开(公告)日：2014-05-06
申请号：US13552083
申请日：2012-07-18
申请人： Steven Y. Ng , Hui Rong Shen , Jorge Heller
发明人： Steven Y. Ng , Hui Rong Shen , Jorge Heller
IPC分类号： A61K31/435 , A61K31/439 , A61K31/53 , A61K47/30 , C07D319/04 , A61K9/00 , A61K47/34
CPC分类号： A61K47/34 , A61K8/85 , A61K8/86 , A61K9/0014 , A61K9/0019 , A61K9/0024 , A61K9/06 , A61K9/1647 , A61K31/439 , A61K31/445 , A61K31/573 , A61K31/765 , A61K45/06 , A61K47/10 , A61Q15/00 , A61Q17/04 , A61Q19/00
摘要： A semi-solid delivery vehicle contains a polyorthoester and an excipient, and a semi-solid pharmaceutical composition contains an active agent and the delivery vehicle. The pharmaceutical composition may be a topical, syringable, or injectable formulation; and is suitable for local delivery of the active agent. Methods of treatment are also disclosed.
摘要翻译： 半固体递送载体含有聚原酸酯和赋形剂，半固体药物组合物含有活性剂和递送载体。 药物组合物可以是局部，注射剂或可注射制剂; 并适用于活性剂的局部递送。 还公开了治疗方法。
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8.发明授权公开(公告)号：US08252306B2
公开(公告)日：2012-08-28
申请号：US13279949
申请日：2011-10-24
申请人： Steven Y. Ng , Hui Rong Shen , Jorge Heller
发明人： Steven Y. Ng , Hui Rong Shen , Jorge Heller
IPC分类号： A61K31/439 , A61K31/435 , A61K31/46 , A61K31/416 , A61K47/30 , A61P1/08 , C07D319/04
CPC分类号： A61K47/34 , A61K8/85 , A61K8/86 , A61K9/0014 , A61K9/0019 , A61K9/0024 , A61K9/06 , A61K9/1647 , A61K31/439 , A61K31/445 , A61K31/573 , A61K31/765 , A61K45/06 , A61K47/10 , A61Q15/00 , A61Q17/04 , A61Q19/00
摘要： A semi-solid delivery vehicle contains a polyorthoester and an excipient, and a semi-solid pharmaceutical composition contains an active agent and the delivery vehicle. The pharmaceutical composition may be a topical, syringable, or injectable formulation; and is suitable for local delivery of the active agent. Methods of treatment are also disclosed.
摘要翻译： 半固体递送载体含有聚原酸酯和赋形剂，半固体药物组合物含有活性剂和递送载体。 药物组合物可以是局部，注射剂或可注射制剂; 并适用于活性剂的局部递送。 还公开了治疗方法。
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9.发明申请Process for Preparing a Semi-Solid Delivery Vehicle and Pharmaceutical Compositions 有权制备半固体输送车辆和药物组合物的方法公开(公告)号：US20120041021A1
公开(公告)日：2012-02-16
申请号：US13279949
申请日：2011-10-24
申请人： Steven Y. Ng , Hui-Rong Shen , Jorge Heller
发明人： Steven Y. Ng , Hui-Rong Shen , Jorge Heller
IPC分类号： A61K31/439 , A61P1/08 , A61K47/34
CPC分类号： A61K47/34 , A61K8/85 , A61K8/86 , A61K9/0014 , A61K9/0019 , A61K9/0024 , A61K9/06 , A61K9/1647 , A61K31/439 , A61K31/445 , A61K31/573 , A61K31/765 , A61K45/06 , A61K47/10 , A61Q15/00 , A61Q17/04 , A61Q19/00
摘要： A semi-solid delivery vehicle contains a polyorthoester and an excipient, and a semi-solid pharmaceutical composition contains an active agent and the delivery vehicle. The pharmaceutical composition may be a topical, syringable, or injectable formulation; and is suitable for local delivery of the active agent. Methods of treatment are also disclosed.
摘要翻译： 半固体递送载体含有聚原酸酯和赋形剂，半固体药物组合物含有活性剂和递送载体。 药物组合物可以是局部，注射剂或可注射制剂; 并适用于活性剂的局部递送。 还公开了治疗方法。
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公开(公告)号：US20100010104A1
公开(公告)日：2010-01-14
申请号：US12564881
申请日：2009-09-22
申请人： Steven Y. Ng , Hui-Rong Shen , Jorge Heller
发明人： Steven Y. Ng , Hui-Rong Shen , Jorge Heller
IPC分类号： A61K47/34
CPC分类号： A61K47/34 , A61K8/85 , A61K8/86 , A61K9/0014 , A61K9/0019 , A61K9/0024 , A61K9/06 , A61K9/1647 , A61K31/439 , A61K31/445 , A61K31/573 , A61K31/765 , A61K45/06 , A61K47/10 , A61Q15/00 , A61Q17/04 , A61Q19/00
摘要： A semi-solid delivery vehicle contains a polyorthoester and an excipient, and a semi-solid pharmaceutical composition contains an active agent and the delivery vehicle. The pharmaceutical composition may be a topical, syringable, or injectable formulation; and is suitable for local delivery of the active agent. Methods of treatment are also disclosed.
摘要翻译： 半固体递送载体含有聚原酸酯和赋形剂，半固体药物组合物含有活性剂和递送载体。 药物组合物可以是局部，注射剂或可注射制剂; 并适用于活性剂的局部递送。 还公开了治疗方法。
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