专利检索 ap:("Subramanian Iyer" OR "William L. Johnson" OR "Lance Nguyen" OR "Steven C. Ross" OR "Ruye Xing") AND inv:"Steven C. Ross" 第 1 页

1.

发明授权
Purified cytokine inhibitory factor 有权

公开(公告)号：US07083809B2

公开(公告)日：2006-08-01

申请号：US10364593

申请日：2003-02-11

申请人： Subramanian Iyer , William L. Johnson , Lance Nguyen , Steven C. Ross , Ruye Xing

发明人： Subramanian Iyer , William L. Johnson , Lance Nguyen , Steven C. Ross , Ruye Xing

IPC分类号： A61K35/54

CPC分类号： A61K35/57 , Y02A50/411

摘要： Disclosed is a composition comprising a substantially purified Cytokine Inhibitory Factor (CIF) having certain characteristics, including the ability to inhibit RNA transcription of the pro-inflammatory cytokines tumor necrosis factor alpha (TNF-α), interleukin-1-beta (IL-1β), and interleukin-2 (IL-2). Also disclosed is a method for substantially purifying the Cytokine Inhibitory Factor and a method for modulating the immune system of an animal using such composition.