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    LIPOSOMAL FORMULATION FOR OCULAR DRUG DELIVERY
    2.
    发明申请
    LIPOSOMAL FORMULATION FOR OCULAR DRUG DELIVERY 审中-公开
    用于药物输送的药物制剂

    公开(公告)号：US20130216606A1

    公开(公告)日：2013-08-22

    申请号：US13816640

    申请日：2011-08-12

    申请人： Subramanian Venkatraman ,  Jayaganesh V. Natarajan ,  Tina Wong ,  Yin Chiang Freddy Boey

    发明人： Subramanian Venkatraman ,  Jayaganesh V. Natarajan ,  Tina Wong ,  Yin Chiang Freddy Boey

    IPC分类号： A61K9/127 ,  A61K31/215

    CPC分类号： A61K9/127 ,  A61K9/0048 ,  A61K31/215 ,  A61K31/5575

    摘要： The present invention is directed to a liposomal formulation for ocular drug delivery comprising (i) liposomes comprising at least one lipid bilayer, and (ii) a prostaglandin drug and/or a prostaglandin derivative associated in the liposomes, wherein the liposomes have a mean diameter of less than 2μπι. The present invention is also directed to a pharmaceutical comprising the liposomal formulation and a method of producing the liposomal formulation for ocular drug delivery. Additionally, the present invention is directed to a method of treating or preventing an ocular disease, comprising administering the liposomal formulation or the pharmaceutical composition to a subject in need thereof.

    摘要翻译： 本发明涉及一种用于眼药物递送的脂质体制剂，其包含（i）包含至少一种脂质双层的脂质体，和（ii）在脂质体中相关的前列腺素药物和/或前列腺素衍生物，其中所述脂质体具有平均直径 小于2mupiiota。 本发明还涉及包含脂质体制剂和生产用于眼药物递送的脂质体制剂的方法的药物。 另外，本发明涉及治疗或预防眼部疾病的方法，包括将脂质体制剂或药物组合物施用于有需要的受试者。