-
公开(公告)号：US20210040062A1
公开(公告)日：2021-02-11
申请号：US16077798
申请日：2017-02-14
发明人： Hiroaki TANAKA , Ayako BOHNO
IPC分类号： C07D401/04
摘要： The present invention provides a compound represented by formula [I′] shown below or a pharmaceutically acceptable salt thereof that has an inhibitory effect on 20-HETE producing enzyme, wherein the structure represented by formula [III] shown below represents any of the structures represented by formula group [IV] shown below, wherein R1 represents a hydrogen atom, a fluorine atom, methyl, etc.; R2, R3, and R4 each independently represent a hydrogen atom, a fluorine atom, or methyl; W represents a single bond, C1-3alkanediyl, or the formula —O—CH2CH2—; and ring A represents (a) substituted C4-6cycloalkyl, (b) substituted 4- to 6-membered saturated nitrogen-containing heterocyclyl, (c) substituted phenyl, (d) substituted pyridyl, (e) substituted 2,3-dihydrobenzofuran, (f) 4- to 6-membered saturated oxygen-containing heterocyclyl, etc.
-
公开(公告)号：US20210122741A1
公开(公告)日：2021-04-29
申请号：US16637595
申请日：2018-08-10
发明人： Hiroaki TANAKA , Madoka KAWAMURA , Makoto HAMADA , Yohei KOBASHI , Yuji ITO , Kazuaki SUZUKI , Ayako BOHNO , Kosuke FUNAYAMA
IPC分类号： C07D405/14 , C07D401/04 , C07D401/14 , C07D409/14 , A61P13/12
摘要： The present invention provides a compound represented by formula [I] shown below or a pharmaceutically acceptable salt thereof that has an inhibitory effect on 20-HETE producing enzyme. (in formula [I] above, the structure represented by formula [II] below: represents any of the structures represented by formula group [III] below: R1, R2, R3, and R4 independently represent a hydrogen atom, a fluorine atom, methyl, or the like, R5 represents any of the structures represented by formula group [IV]:
-
搜索结果
2 条记录 (耗时 0.013 秒)
