公开(公告)号：US20140205672A1

公开(公告)日：2014-07-24

申请号：US14158149

申请日：2014-01-17

Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Inventor： Shigeo Yanai ,  Kazumichi Yamamoto

IPC: A61K9/24 ,  A61K31/4188

CPC classification number: A61K9/209 ,  A61K9/28 ,  A61K31/4188

Abstract: A controlled release composition for oral administration, which comprises a physiologically active substance which is a compound represented by the formula: wherein n is an integer of 1 to 3, and Ar is an aromatic ring which may be substituted, or a salt thereof, and a hydrophilic polymer, or a controlled release composition for oral administration, wherein a core containing the physiologically active substance is coated with a coating layer containing a polymer, is provided.

Abstract translation: 一种用于口服给药的控释组合物，其包含生理活性物质，其为由下式表示的化合物：其中n为1〜3的整数，Ar为可被取代的芳香环，或其盐，以及 亲水性聚合物或用于口服给药的控释组合物，其中含有生理活性物质的核心被包含聚合物的涂层涂覆。