公开(公告)号：US20200157062A1

公开(公告)日：2020-05-21

申请号：US16773720

申请日：2020-01-27

申请人： TAKEDA PHARMACEUTICAL COMPANY LIMITED

发明人： Yoshihiro Banno ,  Masahiro Kamaura ,  Kazuaki Takami ,  Koichiro Fukuda ,  Shigekazu Sasak

IPC分类号： C07D263/46 ,  C07D213/70 ,  A61P27/02 ,  C07D213/65 ,  C07D263/38 ,  C07D239/34 ,  C07D231/22 ,  C07D231/12 ,  A61K31/505 ,  A61K31/4418 ,  A61K31/421 ,  A61K31/415

摘要： Provided is a heterocyclic compound having a superior RBP4-lowering action and useful as a medicament for the prophylaxis or treatment of a disease or symptom mediated by an increase in RBP4 or retinol supplied by RBP4.A compound represented by the formula (I): wherein each symbol is as defined in the Description, or a salt thereof has a superior RBP4-lowering action, and is useful as a medicament for the prophylaxis or treatment of a disease or symptom mediated by an increase in RBP4 or retinol supplied by RBP4.