公开(公告)号：US20220324922A1

公开(公告)日：2022-10-13

申请号：US17851430

申请日：2022-06-28

Applicant: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED

Inventor： Shai BERLIN ,  Ido CARMI ,  Shaden ZOABI

IPC: C07K14/435 ,  A61K48/00 ,  A61P25/28

Abstract: Provided herein are modified forms of Conantokin peptides, including, modified Con-P peptides, nucleic acids encoding the same and compositions thereof. Further provided are nucleic acid molecules encoding for chimeric modified conantokin polypeptides to be expressed in or on a membrane of a target cells, compositions comprising the same and uses thereof for treating various neurodegenerative conditions.