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公开(公告)号:US11332459B2
公开(公告)日:2022-05-17
申请号:US16754349
申请日:2018-10-18
发明人: Michael D. Bartberger , Nagasree Chakka , Hua Gao , Angel Guzman-Perez , Daniel B. Horne , Zihao Hua , Madeleine Kieffer , Daniel C. H. Lin , Benjamin Charles Milgram , Jane Panteleev , Laurie Schenkel , John Stellwagen , Matthew Weiss , Ryan D. White , Wei Zhao
IPC分类号: C07D401/14 , A61K31/4545 , C07D401/04 , C07D403/04 , C07D413/14 , C07D471/04 , C07D471/10 , C07D498/04
摘要: The present invention relates to inhibitors of Transient Receptor Potential Channel 6 (TRPC6) protein activity. The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising a compound of the invention, a method for manufacturing compounds of the invention and therapeutic uses thereof.