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公开(公告)号:US20240100150A1
公开(公告)日:2024-03-28
申请号:US18255612
申请日:2021-12-02
申请人: TEXAS BIOMEDICAL RESEARCH INSTITUTE , Spanish National Centre for Biotechnology , Scripps Research
IPC分类号: A61K39/215 , A61P31/14 , C12N15/70
CPC分类号: A61K39/215 , A61P31/14 , C12N15/70 , A61K2039/53 , C12N2770/20022 , C12N2770/20034 , C12N2770/20062 , C12N2770/20071 , C12N2800/204
摘要: Provided here are compositions for a bacterial artificial chromosome-based construct containing a replication-competent recombinant severe acute respiratory syndrome coronavirus-2 genome and methods of making such compositions and uses thereof.