专利检索 ap:("THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND" OR "UNITED STATES DEPARTMENT OF AGRICULTURE" OR "XAVIER UNIVERSITY OF LOUISIANA") AND inv:"Matthew E. BUROW" 第 1 页

1.

发明申请
NOVEL DAIDZEIN ANALOGS AS TREATMENT FOR CANCER 有权
标题翻译：新型DAIDZEIN模拟物作为癌症治疗

公开(公告)号：US20150148409A1

公开(公告)日：2015-05-28

申请号：US14597252

申请日：2015-01-15

申请人： THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND , UNITED STATES DEPARTMENT OF AGRICULTURE , XAVIER UNIVERSITY OF LOUISIANA

发明人： Guangdi WANG , Matthew E. BUROW , Stephen M. BOUE , Thomas E. WIESE , Quan JIANG

IPC分类号： A61K31/353

CPC分类号： A61K31/353 , A61K31/352 , C07D311/38 , C07D493/04

摘要： Provided are compositions for treatment of cancers, including breast cancer, comprising at least one novel daidzein analog, as well as methods of using the same for preventing or treating cancer or tumor growth.

摘要翻译： 提供了用于治疗包括至少一种新的黄豆苷原类似物的癌症（包括乳腺癌）的组合物，以及用于预防或治疗癌症或肿瘤生长的方法。

2.

发明申请
NOVEL ANTHRANILIC AMIDES AND THE USE THEREOF 有权

公开(公告)号：US20230100458A1

公开(公告)日：2023-03-30

申请号：US17897116

申请日：2022-08-26

申请人： THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND , DUQUESNE UNIVERSITY OF THE HOLY GHOST

发明人： Suravi CHAKRABARTY , Patrick T. FLAHERTY , Darlene MONLISH , Jane E. CAVANAUGH , Matthew E. BUROW , Steven ELLIOTT , Van T. HOANG

IPC分类号： C07D295/16 , C07C229/58 , C07C237/30 , C07C237/32 , C07C237/34 , C07C237/36

摘要： Disclosed are anthranilic amide derivatives having the formula: Compositions are disclosed that include the anthranilic amide derivatives and the use of the anthranilic amide derivatives for the manufacture of a medicament. Further disclosed are methods of inhibiting or treating cancer, inhibiting or reversing an epithelial to mesenchymal cellular transition, and/or inhibiting MEK1/2 and/or MEK 5 enzymatic activity in a subject by administering to the subject an effective amount of a disclosed anthranilic amide derivative.