公开(公告)号：US20220089774A1

公开(公告)日：2022-03-24

申请号：US17310296

申请日：2020-01-29

Applicant: THE ASAN FOUNDATION ,  EDISBIOTECH CO., LTD. ,  UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION

Inventor： Seung-Jae MYUNG ,  Eun-Ju DO ,  Jayoung KANG ,  Hye-Nam SON ,  Hyori KIM ,  A-Neum LEE ,  Yeong Hui CHO

IPC: C07K16/32 ,  G01N33/574

Abstract: The present invention relates to a monoclonal antibody which specifically binds to an EGF2 domain of colon cancer secreted protein-2 (CCSP-2), or an antigen-binding fragment thereof. The monoclonal antibody or the antigen-binding fragment thereof of the present invention specifically binds to the EGF2 domain of CCSP-2, and thus has significantly increased affinity compared with existing peptides specifically binding to CCSP-2 and further increased specificity compared with existing antibodies to CCSP-2. Therefore, in future, accurate diagnosis can be achieved by specific detection of CCSP-2 in the protein level.

公开(公告)号：US20190239730A1

公开(公告)日：2019-08-08

申请号：US16342900

申请日：2017-10-18

Applicant: THE ASAN FOUNDATION

Inventor： Seung-Jae MYUNG ,  Sang-Yeob KIM ,  Sang Mun BAE ,  Eun-Ju DO ,  Dong-Jun BAE

IPC: A61B1/04 ,  A61B1/06 ,  A61B1/31 ,  A61B1/05 ,  G01N21/64

CPC classification number: A61B1/043 ,  A61B1/05 ,  A61B1/0661 ,  A61B1/31 ,  G01N21/64

Abstract: There is disclosed a multi-wavelength endoscopic system for imaging an observation site labeled with a plurality of fluorescent materials having different colors. The system includes an imaging unit configured to acquire image data by polarizing incident light reflected from the observation site in a first direction and a second direction perpendicular to the first direction, dividing a spectrum region of the incident light polarized in the first direction and the second direction into a plurality of spectrum channels and measuring the intensity of light for each of the spectrum channel. The system further includes a computing unit configured to store a single fluorescence spectrum extracted from sample image data obtained by single-treating the observation site with each of the fluorescent materials and configured to separate and output the image data obtained in the imaging unit using the single fluorescence spectrum so that each of the fluorescent materials is displayed separately.