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公开(公告)号:US20210163415A1
公开(公告)日:2021-06-03
申请号:US17167251
申请日:2021-02-04
发明人: KENNETH DARRELL BERLIN , RICHARD A. BUNCE , KRISHNA KUMAR GNANASEKARAN , FIELD M. WATTS, JR. , DONGHUA HOWARD ZHOU
IPC分类号: C07D215/06 , A61P35/00 , C07D335/06 , C07D311/70
摘要: Chemical compounds that inhibit cancer cell growth are provided. The compounds are heteroarotinoids and derivatives thereof with oxygen, nitrogen or sulfur in chroman systems, tetrahydroquinoline systems, and tetrahydrothiochroman systems.
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2.
公开(公告)号:US20200062711A1
公开(公告)日:2020-02-27
申请号:US16549337
申请日:2019-08-23
发明人: KENNETH DARRELL BERLIN , RICHARD A. BUNCE , KRISHNA KUMAR GNANASEKARAN , FIELD M. WATTS, JR. , DONGHUA HOWARD ZHOU
IPC分类号: C07D215/06 , C07D311/70 , C07D335/06 , A61P35/00
摘要: Chemical compounds that inhibit cancer cell growth are provided. The compounds are heteroarotinoids and derivatives thereof with oxygen, nitrogen or sulfur in chroman systems, tetrahydroquinoline systems, and tetrahydrothiochroman systems.
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