公开(公告)号：US11993573B2

公开(公告)日：2024-05-28

申请号：US17167251

申请日：2021-02-04

Applicant: THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY

Inventor： Kenneth Darrell Berlin ,  Richard A. Bunce ,  Krishna Kumar Gnanasekaran ,  Field M. Watts, Jr. ,  Donghua Howard Zhou

IPC: A61P35/00 ,  A61K31/352 ,  A61K31/382 ,  A61K31/47 ,  C07D215/06 ,  C07D311/70 ,  C07D335/06

CPC classification number: C07D215/06 ,  A61K31/352 ,  A61K31/382 ,  A61K31/47 ,  A61P35/00 ,  C07D311/70 ,  C07D335/06

Abstract: Chemical compounds that inhibit cancer cell growth are provided. The compounds are heteroarotinoids and derivatives thereof with oxygen, nitrogen or sulfur in chroman systems, tetrahydroquinoline systems, and tetrahydrothiochroman systems.

公开(公告)号：US10947198B2

公开(公告)日：2021-03-16

申请号：US16549337

申请日：2019-08-23

Applicant: THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY

Inventor： Kenneth Darrell Berlin ,  Richard A. Bunce ,  Krishna Kumar Gnanasekaran ,  Field M. Watts, Jr. ,  Donghua Howard Zhou

IPC: C07D215/06 ,  A61P35/00 ,  C07D335/06 ,  C07D311/70

Abstract: Chemical compounds that inhibit cancer cell growth are provided. The compounds are heteroarotinoids and derivatives thereof with oxygen, nitrogen or sulfur in chroman systems, tetrahydroquinoline systems, and tetrahydrothiochroman systems.