公开(公告)号：US11191778B2

公开(公告)日：2021-12-07

申请号：US16523044

申请日：2019-07-26

Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM

Inventor： Ali Azhdarinia ,  Sukhen C. Ghosh ,  Nathaniel L. Wilganowski ,  Eva M. Sevick-Muraca

IPC: A61K47/64 ,  A61K33/243 ,  A61K33/244 ,  A61K33/24 ,  A61K39/385 ,  A61K39/395 ,  C07K16/28 ,  A61K33/02 ,  A61K49/00 ,  A61K38/16 ,  A61K39/00

Abstract: In some aspects, the present disclosure provides compositions comprising an N4-based MMC ligand, a cell targeting group, and a fluorophore or a therapeutic compound comprising a formula: wherein the variables are as defined herein. In some embodiments, these compositions may be used in the imaging techniques or in the treatment of a disease or disorder such as cancer.

公开(公告)号：US10441607B1

公开(公告)日：2019-10-15

申请号：US15439515

申请日：2017-02-22

Applicant: The Board of Regents of the University of Texas System

Inventor： Ali Azhdarinia ,  Sukhen C. Ghosh ,  Nathaniel L. Wilganowski ,  Eva M. Sevick-Muraca

IPC: A61K38/16 ,  A61K39/385 ,  A61K39/395 ,  A61K33/02 ,  A61K33/24 ,  A61K49/00 ,  A61K39/00

Abstract: In some aspects, the present disclosure provides compositions comprising an N4-based MMC ligand, a cell targeting group, and a fluorophore or a therapeutic compound comprising a formula: wherein the variables are as defined herein. In some embodiments, these compositions may be used in the imaging techniques or in the treatment of a disease or disorder such as cancer.