公开(公告)号：US20190151296A1

公开(公告)日：2019-05-23

申请号：US16097405

申请日：2017-04-28

Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM

Inventor： Maithili P DALVI ,  Elisabeth D MARTINEZ ,  John D MINNA ,  Juan BAYO-FINA ,  Amit DAS

IPC: A61K31/444 ,  A61K31/55 ,  A61K31/337 ,  A61K45/06 ,  A61P35/00 ,  A61N5/10 ,  A61K31/282 ,  A61K33/243

Abstract: Disclosed are methods for the use of Jumonji C demethylase inhibitors for the radiosensitization of cancers cells and the treatment and prevention of chemotherapy resistance in cancer.