公开(公告)号：US20200075151A1

公开(公告)日：2020-03-05

申请号：US16558698

申请日：2019-09-03

Applicant: The Board of Regents of the University of Texas System

Inventor： Troy Long ,  Mingli Chen ,  Steve Jiang ,  Weiguo Lu

IPC: G16H20/40 ,  A61N5/10

Abstract: A method and system for generating a voxel-based quadratic penalty model for automatic intensity modulated radiation therapy (IMRT) treatment planning are disclosed herein. A computing system generates an initial assignment of threshold values to a penalty function for IMRT treatment planning The computing system receives an update to a dose value associated with the IMRT treatment planning The computing system dynamically updates the threshold values based on the updated dose value. The computing system continues to iterate the threshold values based on further updated dose values.

公开(公告)号：US12138479B2

公开(公告)日：2024-11-12

申请号：US17597509

申请日：2020-07-13

Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM

Inventor： Weiguo Lu ,  Xuejun Gu ,  Mingli Chen ,  Xun Jia ,  Steve Bin Jiang

IPC: A61N5/10

Abstract: The present disclosure is directed towards a treatment planning system for use in a stereotactic radiotherapy system. In particular, the disclosed systems and methods may be used for generating a treatment plan and/or verifying an existing treatment plan. Moreover, the disclosed systems and methods may be suitable for use in a clinical setting. A method for verifying a treatment plan of a stereotactic radiotherapy device may include the steps of receiving a treatment plan, generating a second treatment plan by applying a modified monte-carlo method to regions of interest in the treatment plan, and identifying discrepancies between the received treatment plan and the generated second treatment plan.

公开(公告)号：US11651847B2

公开(公告)日：2023-05-16

申请号：US16558698

申请日：2019-09-03

Applicant: The Board of Regents of The University of Texas System

Inventor： Troy Long ,  Mingli Chen ,  Steve Jiang ,  Weiguo Lu

IPC: A61N5/10 ,  G16H20/40

CPC classification number: G16H20/40 ,  A61N5/1031

Abstract: A method and system for generating a voxel-based quadratic penalty model for automatic intensity modulated radiation therapy (IMRT) treatment planning are disclosed herein. A computing system generates an initial assignment of threshold values to a penalty function for IMRT treatment planning. The computing system receives an update to a dose value associated with the IMRT treatment planning. The computing system dynamically updates the threshold values based on the updated dose value. The computing system continues to iterate the threshold values based on further updated dose values.

公开(公告)号：US11065476B2

公开(公告)日：2021-07-20

申请号：US16073097

申请日：2017-01-26

Applicant: The Board of Regents of the University of Texas System

Inventor： Weiguo Lu ,  Mingli Chen ,  Steve B Jiang

IPC: A61N5/10

Abstract: Systems, methods, and computer-readable storage media providing techniques for probing in-vivo beam ranges directly using therapeutic beams for particle therapy treatment are disclosed. In an embodiment, a configuration is determined for one or more probing spots, each spot corresponding to a planned location within an interior region of a tumor volume where a dose of radiation is to be delivered. At least one therapeutic beam is provided to the tumor volume, and one or more images may be captured to provide an indication of the range/depth of the probing spots. Providing the probing spots to the interior of the tumor volume reduces the risk that the dose is provided to sensitive tissue (e.g., because even if the dose is delivered to a location other than the planned location, the dose is likely to remain contained within the tumor volume).