公开(公告)号：US20240132776A1

公开(公告)日：2024-04-25

申请号：US18376348

申请日：2023-10-03

Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS

Inventor： Xiao SU ,  Jemin JEON ,  Johannes ELBERT

IPC: C09K11/06

CPC classification number: C09K11/06 ,  C09K2211/1425 ,  C09K2211/187

Abstract: Chiral redox-polymers that have been enabled for electrochemically-controlled enantioselective interactions. Supramolecular chirality was leveraged for enhancing recognition toward target enantiomers. Chiral redox-metallopolymers were synthesized based on Ugi's amine-inspired chiral monomers, and their enantioselective recognition toward ionic enantiomers, such as tryptophan and naproxen, is demonstrated, with higher enhancement provided by a chiral redox-polymer over a single-site, chiral building block. 2D nuclear magnetic resonance spectroscopy and solid-state circular dichroism support supramolecular chirality resulting from the intramolecular interaction between the ferrocene and the alkyl group in the backbone. The chiral redox-metallopolymers can be used as a platform for electrochemically-modulated enantioselective interactions toward a range of amino acids and pharmaceutical carboxylates.