公开(公告)号：US20140371469A1

公开(公告)日：2014-12-18

申请号：US14308094

申请日：2014-06-18

Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS

Inventor： Pavel Petukhov

IPC: C07D333/24 ,  C07C245/24

CPC classification number: C07D333/24 ,  C07C247/16 ,  C07C247/18

Abstract: The design, modeling, synthesis, biological evaluation, and photoaffinity labeling studies of a series of photoreactive potent and selective HDACs 1 and 2 benzamide based probes are disclosed herein.

Abstract translation: 本文公开了一系列光反应性有效和选择性HDAC 1和2苯甲酰胺基探针的设计，建模，合成，生物学评估和光亲和标记研究。

公开(公告)号：US09108943B2

公开(公告)日：2015-08-18

申请号：US14308094

申请日：2014-06-18

Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS

Inventor： Pavel Petukhov

IPC: C07D333/24 ,  C07C247/16 ,  C07C247/18

CPC classification number: C07D333/24 ,  C07C247/16 ,  C07C247/18

Abstract: The design, modeling, synthesis, biological evaluation, and photoaffinity labeling studies of a series of photoreactive potent and selective HDACs 1 and 2 benzamide based probes are disclosed herein.

Abstract translation: 本文公开了一系列光反应性有效和选择性HDAC 1和2苯甲酰胺基探针的设计，建模，合成，生物学评估和光亲和标记研究。